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The rapid development of new methods for immunological data collection – from multicolor flow cytometry, through single-cell imaging, to deep sequencing – presents us now, for the first time, with the ability to analyze and compare large amounts of immunological data in health, aging and disease. The exponential growth of these datasets, however, challenges the theoretical immunology community to develop methods for data organization and analysis. Furthermore, the need to test hypotheses regarding immune function, and generate predictions regarding the outcomes of medical interventions, necessitates the development of mathematical and computational models covering processes on multiple s...
1946 is the year Bryce DeWitt entered Harvard graduate school. Quantum Gravity was his goal and remained his goal throughout his lifetime until the very end. The pursuit of Quantum Gravity requires a profound understanding of Quantum Physics and Gravitation Physics. As G. A. Vilkovisky commented , "Quantum Gravity is a combination of two words, and one should know both. Bryce understood this as nobody else, and this wisdom is completely unknown to many authors of the flux of papers that we see nowadays." Distingished physicist Cecile DeWitt-Morette skillfully blends her personal and scientific account with a wealth of her late husband's often unpublished writings on the subject matter. This volume, through the perspective of the leading researcher on quantum gravity of his generation, will provide an invaluable source of reference for anyone working in the field.
This volume comprises the most up-to-date account of existing knowledge on the subject of cardiomyopathy and heart failure. Its multidisciplinary approach covers cardiovascular medicine; biochemistry; immunology; molecular biology; virology; epidemiology; and clinical medicine. Cardiomyopathies and Heart Failure: -Covers all major investigational and clinical aspects of the topic; -Provides syntheses as well as reviews; -Offers a unique multidisciplinary and international perspective; -Includes an extensive list of references to relevant work; -Targeted towards practicing physicians and basic researchers.
This two-volume set, LNCS 12565 and 12566, constitutes the refereed proceedings of the 6th International Conference on Machine Learning, Optimization, and Data Science, LOD 2020, held in Siena, Italy, in July 2020. The total of 116 full papers presented in this two-volume post-conference proceedings set was carefully reviewed and selected from 209 submissions. These research articles were written by leading scientists in the fields of machine learning, artificial intelligence, reinforcement learning, computational optimization, and data science presenting a substantial array of ideas, technologies, algorithms, methods, and applications.
Since 1975, the Marcel Grossmann Meetings have been organized to provide opportunities for discussing recent advances in gravitation, general relativity and relativistic field theories, emphasizing mathematical foundations, physical predictions and experimental tests. The objective of these meetings is to facilitate exchange among scientists that may deepen our understanding of space-time structures and to review the status of ongoing experiments aimed at testing Einstein's theory of gravitation from either the ground or space.The Eighth Marcel Grossmann Meeting took place on 22-27 June, 1997, at the Hebrew University of Jerusalem, Israel. The scientific program included 25 plenary talks and 40 parallel sessions during which 400 papers were presented. The papers that appear in this book cover all aspects of gravitation, from mathematical issues to recent observations and experiments.
This book constitutes the post-conference proceedings of the Third International Workshop on Machine Learning, Optimization, and Big Data, MOD 2017, held in Volterra, Italy, in September 2017. The 50 full papers presented were carefully reviewed and selected from 126 submissions. The papers cover topics in the field of machine learning, artificial intelligence, computational optimization and data science presenting a substantial array of ideas, technologies, algorithms, methods and applications.
This book constitutes the refereed proceedings of the 11th International Conference on Artificial Immune Systems, ICARIS 2012, held in Taormia, Italy, in August 2012. The 19 revised selected papers presented were carefully reviewed and selected for inclusion in this book. In addition 4 papers of the workshop on bio and immune inspired algorithms and models for multi-level complex systems are included in this volume. Artificial immune systems (AIS) is a diverse and maturing area of research that bridges the disciplines of immunology, biology, medical science, computer science, physics, mathematics and engineering. The scope of AIS ranges from modelling and simulation of the immune system through to immune-inspired algorithms and in silico, in vitro and in vivo solutions.
This volume contains papers based on talks delivered at the Fourth Workshop on Quantum Field Theory Under the Influence of External Conditions. This series of workshops, held at the Institute for Theoretical Physics of the University of Leipzig, was launched in 1989. The present meeting took place 50 years after Hendrik B Casimir discovered the effect named after him. This effect was found by Casimir in investigating the retarded long range van der Waals forces in colloids and re-expressing them as a change in the vacuum energy of the electromagnetic field. The story of why this work was done was told by Casimir himself at the workshop. A historical account of the development of vacuum energ...
Arti?cial immune systems (AIS) is a diverse and maturing area of research that bridges the disciplines of immunology and engineering. The scope of AIS ranges fromimmune-inspiredalgorithmsandengineeringsolutionsinsoftwareandha- ware, to the understanding of immunology through modeling and simulation of immune system concepts. AIS algorithms have been applied to a wide variety of applications, including computer security, fault tolerance, data mining and optimization. In addition, theoretical aspects of arti?cial and real immune s- tems have been the subject of mathematical and computational models and simulations. The 8th InternationalConference on AIS (ICARIS 2009)built on the success of previous years, providing a forum for a diverse group of AIS researchers to present and discuss their latest results and advances. After two years outside Europe, ICARIS 2009 returned to England, the venue for the ?rst ICARIS back in 2002. This year’s conference was located in the historic city of York, and was held in St. William’s College, the conference venue of York Minster, northern Europe’s largest Gothic cathedral.