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Neurotropic Viral Infections
This second edition is a comprehensive study of the viruses that affect the brain and the central nervous system. Along with a focus on the viruses themselves, it addresses the diseases they cause, current treatments and preventive measures. Also discussed are the unique aspects of how viruses cause disease and why certain hosts are more susceptible (e.g., polymorphisms, age, co-morbidities). Because there are 29 cutting edge chapters, written by experts in the fields, Neurotropic Viral Infections has been divided into two separate volumes. Volume 1, Neurotropic RNA Viruses, includes 14 chapters on RNA viruses that cause human disease of the central nervous system ranging from Bornavirus to ...
Neurotropic Viral Infections
Viral infections of the central nervous system or neurotropic viruses are often lethal. These diseases range from polio and measles, to rabies, Varicella-zoster, Herpes, West Nile, Japanese encephalitis, and AIDS. Such infections have profound public health consequences, and the understanding of these diseases involves understanding the interaction between the nervous system and the immune system. This book shows each individual virus, discussing the diseases they cause and the mechanisms by which they cause and spread those diseases. Detection, treatment and prevention are also discussed. Included is coverage of novel and beneficial uses of neurotropic viruses for gene therapy and tumor lysis. Neurotropic Viral Infection has been written in a style suitable for a wide professional audience, and will appeal to anyone from graduate students and postdocs to clinicians and public health professionals.
Neurotropic Viral Infections
This second edition is a comprehensive study of the viruses that affect the brain and the central nervous system. Along with a focus on the viruses themselves, it addresses the diseases they cause, current treatments and preventive measures. Also discussed are the unique aspects of how viruses cause disease and why certain hosts are more susceptible (e.g., polymorphisms, age, co-morbidities). Because there are 29 cutting edge chapters, written by experts in the fields, Neurotropic Viral Infections has been divided into two separate volumes. Volume 1, Neurotropic RNA Viruses, includes 14 chapters on RNA viruses that cause human disease of the central nervous system ranging from Bornavirus to ...
RNA Viruses
This is the first comprehensive book on human/animal gene responses to RNA viral infections, including prevalent, emerging and re-emerging RNA viruses such as HIV, SARS-CoV, West Nile virus, influenza virus and many others. Human gene responses are reviewed by leading virologists worldwide in the following aspects: (i) the altered gene expression profiles at the transcriptional and translational levels detected with cutting-edge technologies such as cDNA microarray and proteomics; (ii) host innate and adapted immune responses to viral replication in target organs; (iii) virus-activated signal transduction pathways in cell survival, apoptosis and autophagosomal pathways; and (iv) the small in...
Blood-Brain Barrier
The vasculature of the central nervous system (eNS) is characterized by the existence of the blood-brain barrier (BBB), which can be regarded as both an anatomical and physiological phenomenon. The BBB is formed by a complex cellular system of endothelial cells, astroglia, pericytes, perivascular macrophages and a basal membrane, although the anatomic substrate of the BBB is the interendothelial tight junctions that form a continuous sealing. The BBB serves as an exquisitely controlled, functional gate to the eNS. It not only protects the brain from agents in the blood that could impair neurological function, but also controls the influx and efflux of numerous substances to maintain proper h...
RNA Viruses
This is the first comprehensive book on human/animal gene responses to RNA viral infections, including prevalent, emerging and re-emerging RNA viruses such as HIV, SARS-CoV, West Nile virus, influenza virus and many others. Human gene responses are reviewed by leading virologists worldwide in the following aspects: (i) the altered gene expression profiles at the transcriptional and translational levels detected with cutting-edge technologies such as cDNA microarray and proteomics; (ii) host innate and adapted immune responses to viral replication in target organs; (iii) virus-activated signal transduction pathways in cell survival, apoptosis and autophagosomal pathways; and (iv) the small interfering RNA/microRNA-mediated gene silencing pathway, a recently characterized new host defense mechanism against viral infection.
BEST
BEST: Implementing Career Development Activities for Biomedical Research Trainees provides an instructional guide for institutions wanting to create, supplement or improve their career and professional development offerings. Each chapter provides an exclusive perspective from an administrator from the 17 Broadening Experiences in Scientific Training (BEST) institutions. The book can aid institutions who train graduate students in a variety of careers by teaching faculty and staff how to create and implement career development programming, how to highlight the effectiveness of offerings, how to demonstrate that creating a program from scratch is doable, and how to inform faculty and staff on getting institutional buy-in. This is a must-have for graduate school deans and faculty and staff who want to implement and institutionalize career development programing at their institutions. It is also ideal for graduate students and postdocs.
Changing Aspects in Stroke Surgery: Aneurysms, Dissection, Moyamoya angiopathy and EC-IC Bypass
What is arterial dissection? What is Moyamoya angiopathy? What is the state-of-the-art of AVM treatment? Readers will find answers to these questions in this book. They will also be informed about the state-of-the-art treatment in the daily stroke therapy.
Understanding Viruses
Understanding Viruses continues to set the standard for the fundamentals of virology. This classic textbook combines molecular, clinical, and historical aspects of human viral diseases in a new stunning interior design featuring high quality art that will engage readers. Preparing students for their careers, the Third Edition greatly expands on molecular virology and virus families. This practical text also includes the latest information on influenza, global epidemiology statistics, and the recent outbreaks of Zika and Ebola viruses to keep students on the forefront of cutting-edge virology information. Numerous case studies and feature boxes illuminate fascinating research and historical cases stimulate student interest, making the best-selling Understanding Viruses the clear choice in virology. Each new print copy includes Navigate 2 Advantage Access that unlocks a comprehensive and interactive eBook, student practice activities and assessments, a full suite of instructor resources (available to adopting instructors with course ID), and learning analytics reporting tools (available to adopting instructors with course ID).
Bioprinting
Of the 121,000 people on donor lists in the U.S., over 100,000 need kidney transplants and thousands die each year while waiting. Bioprinting aspires to build healthy kidney tissue from a patient's own cells and transplant this to boost failing kidneys without fear of rejection...As the twenty-first century dawned, a handful of inspired scientists tried to use 3D printing to create living human tissue: to 3D print living human cells with a functional organization. Their vision was to restore the health of people with intractable injuries-worn out cartilage, severed nerves,ailing kidneys, failing hearts-the gamut of human frailties. Their modest success energized others to join the quest. Now...
