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Analysis of Single-Cell Data
Carolin Loos introduces two novel approaches for the analysis of single-cell data. Both approaches can be used to study cellular heterogeneity and therefore advance a holistic understanding of biological processes. The first method, ODE constrained mixture modeling, enables the identification of subpopulation structures and sources of variability in single-cell snapshot data. The second method estimates parameters of single-cell time-lapse data using approximate Bayesian computation and is able to exploit the temporal cross-correlation of the data as well as lineage information.
Computational Methods in Systems Biology
This book constitutes the refereed proceedings of the 16th International Conference on Computational Methods in Systems Biology, CMSB 2018, held in BRNO, Czech Republic, in September 2018. The 15 full and 7 short papers presented together with 5 invited talks were carefully reviewed and selected from 46 submissions. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology; parameter and model inference from experimental data; automated parameter and model synthesis; model integration and biological databases; multi-scale modeling and analysis methods; design, analysis, and verification methods for synthetic biology; methods for biomolecular computing and engineered molecular devices. Chapters 3, 9 and 10 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Computational Methods in Systems Biology
This book constitutes the refereed proceedings of the 14th International Conference on Computational Methods in Systems Biology, CMSB 2016, held in Cambridge, UK, in September 2016. The 20 full papers, 3 tool papers and 9 posters presented were carefully reviewed and selected from 37 regular paper submissions. The topics include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology and parallel implementations; model inference from experimental data; model integration from biological databases; multi-scale modeling and analysis methods; and computational approaches for synthetic biology.
Computational Methods in Systems Biology
This book constitutes the refereed proceedings of the 13th International Conference on Computational Methods in Systems Biology, CMSB 2015, held in Nantes, France, in September 2015. The 20 full papers and 2 short papers presented were carefully reviewed and selected from 43 full and 4 short paper submissions. The papers cover a wide range of topics in the analysis of biological systems, networks and data such as model checking, stochastic analysis, hybrid systems, circadian clock, time series data, logic programming, and constraints solving ranging from intercellular to multiscale.
A Process-Centric View on Predictive Maintenance and Fleet Prognostics. Development of a Process Reference Model and a Development Method for Fleet Prognostics to Guide Predictive Maintenance Projects
In the age of digitalization and the fourth industrial revolution, predictive maintenance is becoming increasingly important as a proactive maintenance type. Despite the economic benefits that predictive maintenance generates for companies, its practical application is still in its early stages. This is often due to two prevailing challenges. First, there is a deficiency of knowledge about predictive maintenance and its concrete realization. Second, there is a lack of high quality and rich data of historical machine failures. To increase the representativeness of data, data from several similar machines (i.e. a fleet) should be considered. To foster the effective implementation of predictive...
German Immigrants
A partial reconstruction of Bremen passenger lists based on U.S. sources. Not all Bremen passengers are included; only those giving a specific place of origin in Germany. This is about 21%; those giving only "Germany" as place of origin was about 79%.
Researching the European Court of Justice
The book explores cutting-edge interdisciplinary research strategies for the study of the Court of Justice of the European Union.
Floor Plan Manual Housing
Revised edition of the reference work The Floor Plan Manual Housing has for decades been a seminal work in the field of architecture. In its 5th, revised and expanded edition, approximately 160 international housing projects built after 1945 are documented and analyzed. The focus is on exemplary and transferrable projects, and on innovative and trendsetting concepts. The systematic representation of all projects allows the reader to compare and evaluate various floor plans – and to be inspired by the wealth of ideas and strategies for one’s own design work. The introductory theoretical and historical essays have been newly written or updated, and offer a structured overview of the residential housing typology and its development. Fifth revised edition with new projects and contributions With upgraded visual appearance and a new key color Access to the content is facilitated by various index functions
Croydon and the Great War
The last 200 or so pages of this book are taken up with the alphabetical listing of “The Glorious Dead” (2506), the list of Naval and Military Honours (499), also with names in alphabetical order, and thirdly the names of the Returned Prisoners of War(207). In the case of the Fallen the information provided, where known, includes date, place and circumstances of death, date and place of birth, parents, school attended, regiment/corps in which serving at the time of death, where buried ; any decorations awarded are not shown here but in the Honours list. The 36 plates each contain six passport-size photos of individuals who died. The Honours list shows just name, rank, unit, award and dat...
