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Innate Immunity: Resistance and Disease-Promoting Principles
Our understanding of the complex innate immune response is increasing rapidly. Its role in the protection against viral or bacterial pathogens is essential for the survival of an organism. However, it is equally important to avoid unregulated inflammation because innate immune responses can cause or promote chronic autoinflammatory diseases such as gout, atherosclerosis, type 2 diabetes or certain aspects of the metabolic syndrome. In this book leading international experts in the field of innate immunity share their findings, define the ‚state of the art‘ in this field and evaluate how insight into the molecular basis of these diseases could help in the design of new therapies. A tremendous amount of work on the innate immune response has been done over the last fifteen years, culminating in the 2011 Nobel Prize in Physiology/Medicine awarded for the discoveries of Toll genes in immunity in flies, membrane-bound Toll-like receptors in mammals, and dendritic cells as initiators of adaptive immunity.
Human and Environmental Security
Security has tended to be seen as based on military force, yet this illusion is crumbling, literally and figuratively, before our eyes in the conflict zones of Iraq, Afghanistan and Africa. It is now clear that real human security, defined by the Commission on Human Security as 'protecting vital freedoms', can only be achieved if the full range of issues that underpin human security - including environmental integrity - are addressed. This ground-breaking book, authored by prominent international decision makers, tackles the global human security problem across the range of core issues including terrorism, nuclear proliferation, access to water, food security, loss of biodiversity and climate change. The authors identify the causes of insecurity, articulate the linkages between the different elements of human security and outline an agenda for engaging stakeholders from across the globe in building the foundations of genuine and lasting human security for all nations and all people.This is powerful, necessary, solution-focused reading in these times of peril, global conflict, mass inequity and rampant environmental degradation.
The Developing World
There is an explosion of creativity happening in the developing world right now. Best selling creativity author and keynote speaker Fredrik Härén wanted to understand what this creativity explosion means, what it will lead to and how it will change the world. So he set out to find out. For five years Fredrik Härén went to 18 developing countries (and 8 developed countries) and done more than 200 interviews with people who in some way are involved with business and creativity. He has met with cosmetics executives in Russia, professors in South Africa, creativity consultants in Egypt, IT-journalists in Iran, hotel managers in Dubai, designers in Indonesia, government officials in Thailand ...
The Handbook of Community Safety Gender and Violence Prevention
Violence and insecurity are among the most important issues facing communities in the 21st century. Both family violence and community violence are rapidly rising in the urbanizing nations of theSouth and richer nations are also facing increased concern about the health, social, economic and environmental costs of violence and crime. The Handbook of Community Safety, Gender and Violence Prevention is the first book to gather together research and examples, from a gendered perspective, of local, regional and international interventions that work to prevent crime, violence and insecurity. Case studies of successful initiatives from every continent, in settings that vary from large cities to rural areas, are analysed to provide cross-cultural lessons of what works and what doesn t. The book presents essential practical advice to professionals such as: how to obtain diagnostic information on incidence and impacts of violence; how to develop, maintain and evaluate policies and programmes that can effectively promote community safety; and how to create trust and effectiveness in partnerships.
Medicine Across Borders: Exploration of Grey Zones
Medicine Across Borders provides an interdisciplinary space to discuss the issue of substandard and falsified medical products. Scholars from social and medical sciences collaboratively contribute insight to improving safe medicine access. The circulation of medicines and medical products on the informal market is well-known. Stakeholders, including governmental agencies and biotechnic enterprises, invest much effort in designing and implementing macrolevel interventions to limit the spread of such products. Nevertheless, there is a lack of knowledge and understanding of how informal markets function in everyday medicine access and use. This applies to professionals within and beyond academi...
Women’s Drug Use in Everyday Life
This open access book explores the increasing role of psychoactive substances in contemporary everyday life, focussing on women's use. Drawing on an ethnographic study in Sweden, it uses cultural studies and queer phenomenology to analyse the women’s narratives of drug use relating to themes that encompass social, legal, cultural, embodied and gendered perspectives on drugs in the contemporary Western world. It examines topics such as stigma, happiness, children, the body, gifts, the drug market, medication, sickness and health and also the orientation of themselves towards others, to social and cultural norms, to drug laws and to the substances. It discusses how drug related spaces and directions be analysed in terms of gender and class, and how, in turn, the directions of contemporary society and culture can be affected by drug use. It speaks to academics in Sociology, Criminology, Ethnology, Gender studies, Law and History.
Triple Gold Club
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Why Public Space Matters
'Why Public Space Matters' examines how public space contributes to individual and societal flourishing. Based on thirty-five years of ethnographic fieldwork on plazas, walkways, parks, markets and beaches in the United States, Costa Rica, Argentina, India, Kenya and France, it presents a new understanding of the role of social contact, public culture and affective atmosphere in the creation of places essential to everyday urban life.
Socializing Architecture
At the intersection of architecture, art, public culture, and political theory, Socializing Architecture urges architects and urbanists to mobilize a new public imagination toward a more just and equitable urbanization. Drawn from decades of lived experience, Teddy Cruz and Fonna Forman engage the San Diego–Tijuana border region as a global laboratory to address the central challenges of urbanization today: deepening social and economic inequality, dramatic migratory shifts, explosive urban informality, climate disruption, the thickening of border walls, and the decline of public thinking. Complementing Spatializing Justice, Socializing Architecture is the second part of a two-volume monog...
