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Microbiome Interplay and Control
In complex systems, such as our body or a plant, the host is living together with thousands of microbes, which support the entire system in function and health. The stability of a microbiome is influenced by environmental changes, introduction of microbes and microbial communities, or other factors. As learned in the past, microbial diversity is the key and low-diverse microbiomes often mirror out-of-control situations or disease. It is now our task to understand the molecular principles behind the complex interaction of microbes in, on and around us in order to optimize and control the function of the microbial community – by changing the environment or the addition of the right microorga...
Adaption of Microbial Life to Environmental Extremes
This entirely updated second edition provides an overview on the biology, ecology and biodiversity of extremophiles. Unusual and less explored ecosystems inhabited by extremophiles such as marine hypersaline deeps, extreme cold, desert sands, and man-made clean rooms for spacecraft assembly are presented. An additional focus is put on the role of these highly specialized microorganism in applied research fields, ranging from biotechnology and nanotechnology to astrobiology. Examples such as novel psychrophilic enzymes, compounds from halophiles, and detection strategies for potential extraterrestrial life forms are discussed in detail. The book addresses researchers and advanced students in the fields of microbiology, microbial ecology and biotechnology.
Methods and Applications of Autonomous Experimentation
Autonomous Experimentation is poised to revolutionize scientific experiments at advanced experimental facilities. Whereas previously, human experimenters were burdened with the laborious task of overseeing each measurement, recent advances in mathematics, machine learning and algorithms have alleviated this burden by enabling automated and intelligent decision-making, minimizing the need for human interference. Illustrating theoretical foundations and incorporating practitioners’ first-hand experiences, this book is a practical guide to successful Autonomous Experimentation. Despite the field’s growing potential, there exists numerous myths and misconceptions surrounding Autonomous Experimentation. Combining insights from theorists, machine-learning engineers and applied scientists, this book aims to lay the foundation for future research and widespread adoption within the scientific community. This book is particularly useful for members of the scientific community looking to improve their research methods but also contains additional insights for students and industry professionals interested in the future of the field.
Sovereign Mars
The goal of sending humans to Mars is becoming increasingly technologically feasible, but the prospect of space colonization raises important questions about civilizational ethics and collective morality. History shows how destructive colonialism has been, resulting in centuries-long struggles to achieve liberation from the violent competition for land and resources by colonial powers. Space settlement poses the same temptation on a cosmic scale, with commercial actors and government space agencies doing the work previously carried out by European empires. The question is whether humans will take a different approach in this new frontier. In Sovereign Mars, astrobiologist Jacob Haqq-Misra ar...
Phenomenology and Future Generations
In the face of widespread environmental and social destabilization and growing uncertainty about the future of humanity, this collection of essays brings the philosophical tradition of phenomenology to the question of relations between generations to examine our ethical, political, and environmental obligations to future people. Emphasizing phenomenology's rich reflections on the role of time in the constitution of the social-historical world and its relation to the environment, the essays interweave the central themes of mortality, natality, generativity, and amor mundi to build vital bridges between new developments in both eco- and critical phenomenology and important work in intergenerational ethics. Together, the chapters reevaluate the traditional scope and foundational concepts of environmental ethics and social justice, paving the way for a revised understanding of intergenerational responsibilities, culminating in the key insight that future people are of us. The result is an invaluable conceptual toolkit for phenomenologists, ethicists, theorists, students, and activists concerned with environmental justice and climate ethics.
Archaeal Cell Envelope and Surface Structures
Archaea and Bacteria have complex cell envelopes that play important roles in several vital cellular processes, including serving as a barrier that protects the cytoplasm from the environment. Along with associated proteinaceous structures, cell envelopes also ensure cell stability, promote motility, mediate adherence to biotic and abiotic surfaces, and facilitate communication with the extracellular environment. While some aspects of the biosynthesis and structure of the cell are similar to the three domains of life, archaeal cell envelopes exhibit several unique characteristics. Moreover, recent analyzes have revealed that many features of cell envelopes can vary greatly between distantly ...
Emerging Tools for Emerging Symbioses—Using Genomics Applications to Studying Endophytes
Plants are typically colonized by numerous endophyte species symbiotically without any noticeable disease symptoms. These microbes are abundant, diverse and play critical ecological roles across natural and agricultural ecosystems. Endophytes have attracted the attention of researchers due to their various beneficial effects on plants, especially in agricultural crop species. Genomic tools will enhance our understanding on the growth and nutrition requirements of this host-symbiont relationship. Recent advances in DNA sequencing technologies and bioinformatic pipelines have allowed analyzing the plant microbiome and host-endophyte interaction more effectively with limited bias. Furthermore, various studies have employed and utilized transcriptomic and genomic tools to understand the role of endophytes and their interaction with plant hosts. This electronic book covers various research articles highlighting the important developments on endophytes using transcriptomics, next generation sequencing and genomic tools.
Applied Microbiome Statistics
This unique book officially defines microbiome statistics as a specific new field of statistics and addresses the statistical analysis of correlation, association, interaction, and composition in microbiome research. It also defines the study of the microbiome as a hypothesis-driven experimental science and describes two microbiome research themes and six unique characteristics of microbiome data, as well as investigating challenges for statistical analysis of microbiome data using the standard statistical methods. This book is useful for researchers of biostatistics, ecology, and data analysts. Presents a thorough overview of statistical methods in microbiome statistics of parametric and no...
