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Drawing on the author's extensive personal experience, Medicinal Plants of Asia and the Pacific provides comprehensive coverage of the medicinal plants of the region. Describing more than 300 compounds, the book discusses every important class of natural products while highlighting cutting-edge research and recent developments. With its broa
Kelley/DNA Repair in Cancer Therapy, 2012, 978-0-12-384999-1.
Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases is the second volume in the series, Pharmaceutical Leads from Medicinal Plants. This book includes key pharmacological and chemical evidence to support the selection of promising pre-clinical candidates for the treatment of neurodegenerative diseases. This important addition to the natural product and drug discovery literature contains the history, synonyms, medicinal uses, phytopharmacology, pre-clinical potential, and rationale for each plant selected. By providing critical evaluation of pharmacological data, mechanisms of action, and structural requirements for the development of future neuroprotective ag...
In 1860, Oliver Wendell Holmes pointedly expressed himself to the Massachusetts Medical Society: “I firmly believe that if the whole Material Medica, as now used, could be sunk to the bottom of the sea, it would be all the better for mankind, and all the worst for the fishes.” Should one think the same about the current approach in drug discovery from plants? Probably yes. Despite the spending of billions of US dollars, and three decades of efforts, high-throughput screenings have only allowed the discovery of a couple of drugs. One could have reasonably expected the discovery of an arsenal of drugs from the millions of plant extracts randomly tested, but “hits” can be inactive in vitro or too toxic, some molecules need to be metabolized first to be active, and false-positive and false-negative results are common. The bitter truth is that the robotic approach in discovering drugs from plants has proven, to date, its inability to excavate the hundreds of molecules that will contribute to the health progress of Man. However, one can reasonably see that the last patches of primary rainforest on earth hold still hundreds of spectacularly active drugs that await discovery.
Asian medicinal plants show great promise in pharmaceutical and cosmetological development. Researchers engaged in the discovery of new leads in these areas need robust conceptual tools and understanding of interrelated basics of botany, ethnobotany, biomolecular pharmacology, phytochemistry, and medicinal chemistry to guide their investigations. Medicinal Plants of China, Korea, and Japan: Bioresources for Tomorrow’s Drugs and Cosmetics explores the fundamental science and demonstrates the compelling potential of these versatile plants, providing an essential resource to stimulate and guide focused inquiry. It is essential that researchers appreciate the chemotaxonomical statuses of these...
Medicinal Plants of Bangladesh and West Bengal is a complete compendium. It provides the scientific name, classification, local name(s), historical background, local medicinal uses, botanical description, chemical constituents, pharmacological activity and toxicology of more than 100 medicinal spices used in Bengal. Chemical structures of active constituents are provided as well as numerous references. This book is an indispensable tool for researchers, as well as graduates in various disciplines, including pharmacy, pharmacology, medicine, biotechnology, nutrition, cosmetology and drug development. It is also suitable for anyone who is looking for natural products as leads to be developed i...
Asian medicinal plants show great promise in pharmaceutical and cosmetological development. Researchers engaged in the discovery of new leads in these areas need robust conceptual tools and understanding of interrelated basics of botany, ethnobotany, biomolecular pharmacology, phytochemistry, and medicinal chemistry to guide their investigations. M
Medicinal Plants in Asia for Metabolic Syndrome: Natural Products and Molecular Basis offers an in-depth view into the metabolic syndrome pharmacology of natural products with an emphasis on their molecular basis, cellular pathways, metabolic organs, and endocrine regulations. This sensational volume provides the scientific names, botanical classifications, botanical descriptions, medicinal uses, chemical constituents, and pharmacological activities of more than 100 Asian plants, with high quality original botanical plates, chemical structures, and pharmacological diagrams. It also lists hundreds of carefully selected bibliographical references, constituents on insulin resistance, obesity, atherosclerosis, atherogenic dyslipidemia, and endothelial dysfunction.
"This specialist volume details 290 medicinal plant species from areas as diverse as East Africa to Western USA; importantly it comprehensively correlates their botany, ethnomedicine, natural product chemistry and biosynthesis, pharmacological properties and pharmaceutical potential."--Foreword.