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Cancer Informatics
Cancer Informatics chronicles the development of the National Cancer Institute's new Cancer Informatics Infrastructure (CII) - an information management system infrastructure designed to faciliate clinical trials, provide for reliable, secure information exchange, and improve patient care. The book details the challenges involved in creating and managing such a knowledge base, including technologies, standards, and current, state-of-the-art applications. The ultimate goal of CII is to function as an enabler of clinical trials, expediting the clinical trials lifecycle, faciliating faster and safer drug development and more appropriate treatment choices for cancer patients. Contributors address the role the CII must play in converting the growing knowledge of genes, proteins, and pathways into appropriate preventative, diagnostic, and therapeutic measures. Presented in four sections, the first provides an overview of the processes involved in moving the infrastructure for cancer from theory into practice. Sections two through four offer the latest work done in the areas of technology, cancer-specific and national standards, and applications to faciliate clinical trials.
The Foundation of Precision Medicine: Integration of Electronic Health Records with Genomics Through Basic, Clinical, and Translational Research
This eBook contains the 19 articles that were part of a Special Topic in Frontiers in Genetics entitled “Genetics Research in Electronic Health Records Linked to DNA Biobanks”. The Special Issue was published on-line in 2014-2015 and contained papers representing the diverse research ongoing in the integration of electronic health records (EHR) with genomics through basic, clinical, and translational research. We have divided the eBook into four Chapters. Chapter 1 describes the Electronic Medical Records and Genomics (eMERGE) network and its contri-bution to genomics. It highlights methodological questions related to large data sets such as imputation and population stratification. Chap...
Health Informatics Meets EHealth
Progress in medicine has traditionally relied heavily on classical research pathways involving randomized clinical trials (RCTs) to establish reliable evidence for any given therapeutic intervention. However, not only are RCTs lengthy and expensive, they have a number of other disadvantages, including the fact that they are currently failing to keep pace with the number of potential innovative treatment options being developed, particularly in areas such as rare diseases. With the vast amount of data increasingly available for use in profiling patient characteristics and establishing correlations between outcomes and potential predictors, predictive modeling may offer a potential solution to...
Mirror of Parliament
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MEDINFO 2015: EHealth-enabled Health
Health and Biomedical Informatics is a rapidly evolving multidisciplinary field; one in which new developments may prove crucial in meeting the challenge of providing cost-effective, patient-centered healthcare worldwide. This book presents the proceedings of MEDINFO 2015, held in São Paulo, Brazil, in August 2015. The theme of this conference is ‘eHealth-enabled Health’, and the broad spectrum of topics covered ranges from emerging methodologies to successful implementations of innovative applications, integration and evaluation of eHealth systems and solutions. Included here are 178 full papers and 248 poster abstracts, selected after a rigorous review process from nearly 800 submissi...
Computational Intelligence in Medical Decision Making and Diagnosis
Computation intelligence (CI) paradigms, including artificial neural networks, fuzzy systems, evolutionary computing techniques, and intelligent agents, form the basis of making clinical decisions. This book explains different aspects of the current research on CI technologies applied in the field of medical diagnosis. It discusses critical issues related to medical diagnosis, like uncertainties in the medical domain, problems in the medical data, especially dealing with time-stamped data, and knowledge acquisition. Features: Introduces recent applications of new computational intelligence technologies focusing on medical diagnosis issues. Reviews multidisciplinary research in health care, l...
A Hazardous Inquiry
Love Canal--a community poisoned by toxic waste. Borrowing the multi-viewpoint technique of the classic Japanese film RASHOMON, sociologist/engineer Allan Mazur reveals that there are many--often conflicting--versions of what occurred at Love Canal. His collection of gripping personal tales tells how politics, journalism, and epidemiology often clash, when confronting a potential community disaster.
Virtual Knowledge
An examination of emerging forms of knowledge creation using Web-based technologies, analyzed from an interdisciplinary perspective.
News
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