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Quality by design (QbD) is becoming an integral element of the modern pharmaceutical and chemical development approach. In this book, the future ramifications of emergent modern applications of QbD and green analytical chemistry in drug design, process analytical technologies, and bioanalytical process development instruments are discussed. It will reveal and improve the QbD principles used in bioanalysis, process development, downstream processing, and the combination of QbD and green analytical chemistry employing eco-friendly and green solvents for product development. In addition, it will provide complete information regarding applying the QbD concept and ideology to quality control and process development. The book will be beneficial to PhD research scholars, researchers, and postgraduate and undergraduate students of pharmacy and chemical sciences for understanding the concept of quality by design and green chemistry for drug design, as it illustrates the necessary inputs that are related to product quality and, ultimately, process sustainability.
A guide to choosing and using the right techniques High-speed computers and prepackaged statistical routines would seem to take much of the guesswork out of statistical analysis and lend its applications readily accessible to all. Yet, as Phillip Good and James Hardin persuasively argue, statistical software no more makes one a statistician than a scalpel makes one a surgeon. Choosing the proper technique and understanding the analytical context is of paramount importance to the proper application of statistics. The highly readable Common Errors in Statistics (and How to Avoid Them) provides both newly minted academics and professionals who use statistics in their work with a handy field gui...
Praise for Common Errors in Statistics (and How to Avoid Them) "A very engaging and valuable book for all who use statistics in any setting." CHOICE "Addresses popular mistakes often made in data collection and provides an indispensable guide to accurate statistical analysis and reporting. The authors' emphasis on careful practice, combined with a focus on the development of solutions, reveals the true value of statistics when applied correctly in any area of research." MAA Reviews Common Errors in Statistics (and How to Avoid Them), Fourth Edition provides a mathematically rigorous, yet readily accessible foundation in statistics for experienced readers as well as students learning to desig...
Selection bias can, and does, occur, even in randomized clinical trials. Steps need to be taken in order to ensure that this does not compromise the integrity of clinical trials; hence “Selection Bias and Covariate Imbalances in Randomized Clinical Trials” offers a comprehensive treatment of the subject and the methodology involved. This book: Provides an overview of the hierarchy of study designs, and justifies the position of randomised trials at the top of this hierarchy. Discusses the strengths and defects of randomisation, and provides real evidence to justify concern regarding its defects. Outlays the damaging consequences that selection bias causes when it does occur. Considers co...
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Firefighting is combat and should be viewed as a warrior's calling. Firefighters put themselves in harm's way to protect others, a selflessness rooted in the same noble drive as the military warriors who defend our nation. This book about combat is meant to be a guide for those who seek to follow a warrior's path, the path of the fire service warrior. Today's firefighter must be a warrior who will unflinchingly put his very life in harm's way to accomplish a mission, but who is also fully informed about the path being chosen. Embracing the philosophy of the fire service warrior, and striving for the ready position--the synthesis of physical and mental readiness that allows for optimum fireground performance--can reduce firefighter injuries and fatalities. The Combat Position: Achieving Firefighter Readiness will be an invaluable tool for firefighters, company officers, chief officers, and instructors.
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This book examines the experiences of global healthcare workers during the COVID-19 pandemic. It shines a light on the experiences of healthcare workers during the pandemic, exploring their lived experiences of delivering care without losing sight of the emotional and symbolic nature of their work. Incorporating cutting-edge research from global experts in medical anthropology, medical sociology, medicine, psychology and nursing, it uniquely demonstrates the value of rapid qualitative research during infectious epidemics. Drawing on data collected during the COVID-19 pandemic, the book explores global healthcare policies and healthcare workers’ experiences across 20 countries.