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Welcome to the world of The Nacullians, three generations of one family, living in a brick house in a line of other brick houses. Craig Jordan-Baker's dark comedy charts the tensions and traumas of one family and their relationship with the city they inhabit.
Jordan Major is a hit man, an assassin. Call him what you will, he kills people for pay. Soon after his most recent foray, he comes downstairs one morning to find a man he vaguely recognizes in the main room of his virtually impenetrable house. A man, he quickly learns, he killed two years previously. Craig, now a ghost, wants to know who hired Jordan to murder him. What they find out and how they deal with the information will, potentially, set Jordan on a new course. One where he's willing to take out people who deserve his attention, not innocents he’s been hired to kill. At least that's what Craig hopes as he tries to persuade Jordan there are worse things in life than giving up his very lucrative, if highly illegal, occupation. After all, he has his antique store, which brings in more money than he really needs, given what he's stashed in an off-shore bank account. Then NOPD detective Kirk Ireland enters the picture and Jordan's life changes again.
In this memoir, the Chicago Bulls basketball star details his life on the court as an athlete and off the court as an activist. As a member of the 1992 world-champion Chicago Bulls, a dashiki-clad Hodges delivered a handwritten letter to President George H. W. Bush demanding that he do more to address racism and economic inequality. Hodges was also a vocal union activist, initiated a boycott against Nike, and spoke out forcefully against police brutality in the wake of the Rodney King beating. But his outspokenness cost him dearly. In the prime of his career, after ten NBA seasons, Hodges was blackballed from the NBA for using his platform as a professional athlete to stand up for justice. I...
Interleukins are a family of proteins that regulate the maturation, diff- entiation, or activation of cells involved in immunity and inflammation, and belong to a broader family termed cytokines. Collectively these proteins are the key orchestrators of host defense and the response to tissue injury. There are currently 23 different interleukins (numbered from IL-1 to IL-23), although the full extent of the interleukin family will only become clear upon analysis of the human genome sequence. Most important, interleukins are central to the pathogenesis of a wide range of diseases that involve an immune com- nent, including such conditions as rheumatoid arthritis, multiple sclerosis, ulcerative...
Over the past 20 years, technological advances in molecular biology have proven invaluable to the understanding of the pathogenesis of human cancer. The application of molecular technology to the study of cancer has not only led to advances in tumor diagnosis, but has also provided markers for the assessment of prognosis and disease progression. The aim of Molecular Ana- sis of Cancer is to provide a comprehensive collection of the most up-to-date techniques for the detection of molecular changes in human cancer. Leading researchers in the field have contributed chapters detailing practical pro- dures for a wide range of state-of-the-art techniques. Molecular Analysis of Cancer includes chap...
Rubor (redness), tumor (swelling), calor (heat), and dolor (pain) are the classical signs of inflammation. These features are obvious in the skin, where injury or disease causes flare, wheal, and painful burning sensations. Vasodi- tation underlies the flare and heat, plasma exudation the swelling, and acti- tion of sensory nerves relays pain. In chronic conditions, skin biopsies show inflammatory cell infiltrate. Inflammation is not unique to the skin and contr- utes to disease and repair processes in other organ systems in the body. From the viewpoint of this volume, lung inflammation is now recognized as central to the pathophysiology of a number of severe respiratory conditions, the two ...
Parkinson’s disease is a progressive neurodegenerative disorder charact- ized clinically by tremor, rigidity, slow movements, and postural instability. Pathologically, dopaminergic neurons of the substantia nigra bear the brunt of the degeneration, though other neuronal groups can be affected as well. Although Parkinson’s disease is the only neurodegenerative disorder for which effective therapies are available, these treatment options are only symptomatic, do not influence the underlying degenerative process, and are associated with a high incidence of complications, particularly with their long-term use. The progressive nature of the disease and the limitations of its palliative therap...
Follow a former teacher, now a Forensic Psychology Practitioner on a compelling, shocking, thrilling, and potentially explosive adventure that took place over sixteen years in Canada, South Korea, North Korea (DMZ), Japan, France, and the United Kingdom. This true account included twenty-two police forces, the FBI, the regional director of security for Asia Pacific, three embassies, the United States military, the Korean military, millionaires, and a psychopath or two. The crime spree by certain individuals included stalking, cyberstalking, extortion attempts, terrorism, hacking and cracking, breaking and entering, theft, fraud, threats, damage to property, theft of intellectual property, assault, assault causing bodily harm, psychological torture, criminal harassment, and two possible murder attempts. It is your job to examine the facts and to determine who the guilty parties are! Listen to police recordings and view evidence that can be copied and pasted into your browser by following the link at the back of the book.
This book is about melanoma—its biology, immunology, and pathology, as well as the initial use of powerful genomic tools to study its fundamental mole- lar and genetic characteristics. The study of cancer will be profoundly impacted by the Human Genome Project. I would like to discuss some of these changes. The first draft of the human genome sequence was announced in June 2000, and we have just scratched the surface of the changes it will engender in medicine. A relevant question is what are the long-term effects of the Human Genome Project for medicine? I would argue that there are three, and each of these three point toward the view that systems biology will dominate biology and medicin...
The aim of this book is to provide detailed protocols for studying the molecular biology of the pathogen Mycobacterium tuberculosis, and its int- actions with host cells. As established mycobacterial laboratories move - wards exploiting the genome, and laboratories with expertise in other fields apply them to mycobacteria, both traditional and novel methodologies need to be reviewed. Thus the chapters in Mycobacterium tuberculosis Protocols range from perspectives on storage of strains and safety issues to the application of the latest functional genomics technologies. The last few years have been remarkable ones for research into M. tuber- losis. The most important landmark by far has been ...