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This book describes the identification and characterization of genetic loci that determine susceptibility to liver, mammary, or skin carcinogenesis in rodents. It focuses on protein kinases and phospholipases, and stress-related signal transduction.
In the nearly three years that have elapsed since our first Philadelphia Symposium on Aging, our activities and interactions have expanded. We spent no small amount of time discussing the selection of a timely topic for our next symposium. For the first symposium, a variety of topics relating to the study of aging, ranging from phenomena at the cellular level to phenomena in disease states, were selected for consideration. For the present symposium, we thought it more desirable to concentrate on one area only, in order to summarize available information, discover what shortcomings exist, and suggest new directions for research. The paucity of in formation on pharmacological studies in aging ...