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The current epidemic of diabetes, obesity and related disorders is a driving force in the development of new technologies. Technological advances offer great new opportunities for the treatment of these chronic diseases. This review presents an update of developments that promise to revolutionize the treatment of diabetes. It examines hospital and outpatient care, intensive insulin therapy, blood glucose monitoring and innovative steps towards the construction of an artificial pancreas. Providing a comprehensive overview on the latest advances, this volume of Frontiers in Diabetes will be of particular interest to all healthcare providers involved in the daily management of patients with diabetes or related diseases.
We are in the midst of an unprecedented era of rapid scientific and technological advances that are transforming the way our foods are produced and consumed. Food architecture is being used to construct healthier, tastier, and more sustainable foods. Functional foods are being created to combat chronic diseases such as obesity, cancer, diabetes, stroke, and heart disease. These foods are fortified with nutraceuticals or probiotics to improve our mood, performance, and health. The behavior of foods inside our guts is being controlled to increase their healthiness. Precision nutrition is being used to tailor diets to our unique genetic profiles, microbiomes, and metabolisms. Gene editing, nano...
This book is designed to be a ready reckoner on commonly used medications for the treatment of diabetes mellitus. Divided into 17 sections, topics include incretin-based therapies, insulin, chloroquine, metformin, colesevelam, drugs targeting renal excretion of glucose, management of dyslipidaemia, and more. The book concludes with discussion on associated comorbidities such as hypertension and diabetes in the elderly. Drug classes featured are all approved in-line with FDA (United States Food and Drug Administration) guidelines. Authored by recognised, US-based experts in the field, the comprehensive text is further enhanced by clinical photographs, diagrams and tables. Key points Comprehensive guide to pharmaceutical treatments for diabetes mellitus Features approved drugs in-line with FDA (United States Food and Drug Administration) guidelines Includes discussion on commonly associated comorbidities such as hypertension, and diabetes in the elderly Internationally recognised, US-based author team
Medicinal chemistry is a complex science that lies at the very heart of drug discovery. Poor solubility, complex metabolism, tissue retention and slow elimination are just some of the properties of investigational compounds that present a challenge to the design and conduct of ADMET studies. Medicinal chemistry experience and knowledge relating to how a lead structure was modified to solve a specific problem is generally very challenging to retrieve. Presented in a visual and accessible style, this book provides rapid solutions to overcome the universal challenges to optimizing ADMET.
Diabetes doesn’t have to slow you down. Whether you’re a recreational exerciser or a competitive athlete, The Athlete’s Guide to Diabetes has the training and performance advice you need to remain active while effectively managing your condition. Renowned researcher and diabetes expert Dr. Sheri Colberg offers best practices and tips for managing blood glucose levels for athletes of all ages with type 1 and type 2 diabetes. She provides the most up-to-date information on insulin and other medications and their effects on exercise, nutritional practices and supplements, including low-carbohydrate eating, the latest technologies used to manage glucose, including continuous glucose monito...
Issues related to nutrition are among the most pressing public health concerns in modern times. Worldwide, malnutrition affects nearly 1 billion individuals, or more than one in seven people. Many Protein-energy malnutrition and micronutrient deficiencies play roles in more than half of all childhood deaths. Effects of malnutrition include mortality, decreased economic productivity, morbidities, such as blindness and stunting, and development of chronic diseases. With a unique focus on Global Health, this book is a comprehensive introduction to Public Health Nutrition. Designed for MPH programs, this book will prepare students to become successful global public health professionals, with a c...
The thesis focuses on the control of blood glucose devices and design of implantable devices, and offers valuable insights on diabetes mellitus and related physiology and treatments. Diabetes mellitus is a widespread chronic disease in the modern world that affects millions of people around the globe. In Singapore, one in ten of the population has diabetes, and the severity of the problem has prompted the country’s prime minister to talk about the disease at the National Day Rally in 2017. Designing an artificial pancreas that can provide effective blood glucose control for individuals with diabetes is one of the most challenging engineering problems. The author reports on research into th...
Hypoglycaemia, leading to confusion and impaired consciousness, isone of the most feared complications ofdiabetes. Hypoglycaemia in Clinical Diabetes, SecondEdition explains the situations in which it arises and howto manage patients to minimize its occurrence. Fully revised andupdated, the Second Edition of this practical book addresses allaspects of the clinical management of hypoglycaemia. Features new chapters on hypoglycaemia in Type 2 diabetes, theelderly and nocturnal occurrence, as well as prevention and bloodglucose monitoring for detection of hypoglycaemia Edited by two diabetologists with strong internationalreputations who have made significant contributions to ourunderstanding o...
Over three editions the Textbook of Diabetes has built a reputation as a book that is extremely well-organized and easy to navigate, with exceptional illustrations and an excellent blend of clinical and scientific content. Previously edited by John Pickup and Gareth Williams this fourth edition has four brand new editors from across the globe. The editors have assembled an outstanding set of international contributors who provide insight on new developments in diabetes care and information on the latest treatment modalities used around the world. The new Textbook of Diabetes has been restructured into 12 parts in one accessible volume and is designed with the busy diabetes care team in mind....
This issue of Endocrinology Clinics brings the reader up to date on the important advances in research surrounding the neuroendocrine control of metabolism. Guest edited by Christoph Buettner, the topics covered include leptin signaling, hypothalamic inflammation, hypoglycemia awareness, perinatal programming of metabolic disease, substrates, and more.