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A Clinician's Pearls & Myths in Rheumatology
Important strides have been made in understanding the pathophysiologic basis of many inflammatory conditions in recent years, but rheumatology remains a discipline in which diagnosis is rooted in the medical history skillfully extracted from the patient, the careful physical examination, and the discriminating use of laboratory tests and imaging. Moreover, selection of the most appropriate therapy for patients with rheumatic diseases also remains heavily reliant upon clinical experience. Medical disciplines such as rheumatology that depend significantly upon clinical wisdom are prone to the development of systems of ‘Pearls’ and ‘Myths,’ related to the diseases they call their own, a ‘Pearl’ being a nugget of truth about the diagnosis or treatment of a particular disease that has been gained by dint of clinical experience and a ‘Myth’ being a commonly held belief that influences the practice of many clinicians – but is false. This book will pool together the clinical wisdom of seasoned, expert rheumatologists who participate in the care of patients with autoimmune diseases, systemic inflammatory disorders, and all other rheumatic conditions.
Quantum Cosmology
Consequences of quantum gravity on grander scales are expected to be enormous: only such a theory can show how black holes really behave and where our universe came from. Applications of loop quantum gravity to cosmology have especially by now shed much light on cosmic evolution of a universe in a fundamental, microscopic description. Modern techniques are explained in this book which demonstrate how the universe could have come from a non-singular phase before the big bang, how equations for the evolution of structure can be derived, but also what fundamental limitations remain to our knowledge of the universe before the big bang. The following topics will be covered in this book: Hamiltoni...
The Pharmacology of Alcohol and Alcohol Dependence
This is a comprehensive review of the pharmacological effects of alcohol and the mechanisms underlying the pathogenesis of alcoholism. The book draws on general pharmacology, neuropharmacology, and alcohol studies to explore its theme. The second volume in the ALCOHOL AND ALCOHOLISM series, it focuses on the pharmacologic mechanisms underlying the development of alcoholism. The first section on basic pharmacology is concerned with those aspects that are common to all of alcohol's effects. These include pharmacokinetics, general metabolism, and cross-tolerance. The second section on neuropharmacology describes the effects of alcohol on various brain functions, including circulation and metabolism. The third section provides an in-depth review of the neurobiology of physical dependence, withdrawal, and physiological tolerance. The book as a whole gives a comprehensive and authoritative picture of the complex pharmacologic actions of alcohol, particularly on the nervous system. For clinicians and researchers in the field of alcohol and alcoholism, it will serve as a fundamental reference.
Emerging Biofuels
Emerging Biofuels: Stationary and Mobile Applications presents a comprehensive assessment of supply chains and conversion pathways of the promising biofuels in the 21st century. Highlighting the potential of emerging biofuels, the book covers the latest breakthroughs and process intensification strategies for the development of near to mid-term commercialization. Chapters provide readers with an overview of emerging biofuels, key advantages, and major drivers for the biofuel industry. The majority of the book is dedicated to assessing each emerging biofuel, including renewable diesel, bio-CNG, 3rd generation lignocellulosic ethanol, fisher-tropsch biofuels, biohydrogen, microalgal biodiesel,...
The Biology of Alcoholism
The previous volume, The Pathogenesis of Alcoholism: Psychosocial Factors, attempted to describe the interaction of biological, psychological, and social factors that lead to the initiation and perpetuation of alcoholism. The preface to that volume presented our particular view of the bio-. psycho-social interaction as a progressive process in which earlier developments produce new pathogenetic mechanisms, which in turn lead to still other cyclical feedback activities. Although influences from each of the three phenomenologic levels are at work during each stage of the clinical course, it would appear that social factors are most significant in the early phase, psychological factors at the i...
Skin and Connective Tissue Diseases: Advances in Research and Treatment: 2011 Edition
Skin and Connective Tissue Diseases: Advances in Research and Treatment: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Skin and Connective Tissue Diseases. The editors have built Skin and Connective Tissue Diseases: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Skin and Connective Tissue Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Skin and Connective Tissue Diseases: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Debating Environmental Regimes
A consistently high-profile issue, oversight of earth's resources and environment is important to all people. The debate rages, pitting the needs of business against the desires of environmentalists. Although numerous summits have occurred to formulate international policy on this topic, a solution has proven elusive. This book compiles a selection of articles studying the implications of such summits and the importance of environmental regulation in general.
Molecular Level Atomistic and Structural Insights on Biological Macromolecules, Inhibition, and Dynamics Studies
Everything in a living organism relies on biological macromolecules, which have the role of enzymatic chemical transformations, formation of structures, transportation, catalysis, and regulation of biological processes. They are complex biological structures that require an atomistic understanding. A molecular understanding of biological macromolecules has had a massive impact on the pharmaceutical, biotechnological, and chemical industries. Specifically, new enzymatic structures are being discovered through various experimental and computational methods, by describing an atomistic-level insight into function, mechanism, role in reactions and their inhibition. Those atom-level illustrations are mainly focused through enzyme kinetics, enzyme inhibition, mutational and conformational analysis through quantum mechanical and molecular dynamics methods.
Biological Effects of Alcohol
The disease of alcoholism has long been a major health problem which affects significant proportions of the populations of various countries. It is now apparent that legal and moral sanctions have not provided a sufficient impetus to arrest this rampant problem. Therefore, it is evident that the approach to this international health problem must rely on the development of efficacious prevention and treatment techniques. If the treatment and prevention of alcoholism is to be based on the rational assessment of the disease, it is imperative that we understand the complex determinants of this disease. The elements that initiate and perpetuate this addictive process must be examined and elucidat...
Introduction to Clinical Pharmacology
This textbook is built around patient presentation, advancing from symptoms through diagnosis to treatment as anticipated in clinical practice. As a result, this textbook provides concise, focused information on pharmacological treatments and mechanisms of action related to specific symptoms and patient presentation. Each chapter is followed by relevant cases and questions with answers and detailed explanations. The book will be of use to medical, pharmacy, pharmacology and physiology students, practicing physicians and pharmacists, and pre-medical students preparing for a Medical College Admission Test (MCAT) in the United States and similar tests offered in other countries. The readers are given a guided presentation of how practicing physicians think when facing symptoms and determining treatments.
