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The Promised Lands
They were, in the words of one contemporary observer, "the Promised Lands." In all of Europe, only Northern Italy could rival the economic power and cultural wealth of the Low Countries in the later Middle Ages. In The Promised Lands, Wim Blockmans and Walter Prevenier trace the relations between the cultural and economic developments of the Low Countries and the political evolution of the region under the rule of the dukes of Burgundy. Combining political, diplomatic, administrative, economic, social, artistic, and cultural history, Blockmans and Prevenier have synthesized the most recent research on the subject—much of it their own—to produce the most accessible and authoritative book in English on the subject. This is an updated and revised translation of a classic work first published in 1988, now expanded and reoriented toward a broader international readership.
Agrammatic Aphasia
This major reference work fills a need long recognized in neurolinguistics: a source for analyzable speech transcripts from agrammatic aphasic patients that provides detailed grammatical descriptions and distributional analyses. This 3-volume set is unique in that it presents narrative speech from carefully selected clinically comparable patients, speakers of 14 languages, and parallel narratives by normal speakers. For each of the 14 languages there is a case presentation chapter analyzing and discussing the language of agrammatic patients, followed by primary data, which are organized as follows: running text of speech by two patients; interlinear morphemic translations of those texts; run...
Frontiers in Anti-Cancer Drug Discovery
Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest and the most important advances in anti-cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. Each volume is devoted to the major advances in anti-cancer drug design and discovery. The book series is essentia...
Law and Long-Term Economic Change
This edited volume provides a unique multidisciplinary perspective on the relationship between legal regimes and long-term economic development across major civilizations in Eurasia.
Daughters of Edward I
A colorful biography of five royal sisters in medieval England. In 1254 the teenage heir to the English throne took a Spanish bride, the sister of the king of Castile, in Burgos. Their marriage of thirty-six years proved to be one of the great royal romances of the Middle Ages. Edward I of England and Leonor of Castile had at least fourteen children together, though only six survived into adulthood, five of them daughters. Daughters of Edward I traces the lives of these five capable, independent women, including Joan of Acre, born in the Holy Land, who defied her father by marrying a second husband of her own choice, and Mary, who did not let her forced veiling as a nun stand in the way of the life she really wanted to live. These women’s stories span the decades from the 1260s to the 1330s, through the long reign of their father, the turbulent reign of their brother Edward II, and into the reign of their nephew, the child-king Edward III.
Antibiotic Resistance
This book describes antibiotic resistance amongst pathogenic bacteria. It starts with an overview of the erosion of the efficacy of antibiotics by resistance and the decrease in the rate of replacement of redundant compounds. The origins of antibiotic resistance are then described. It is proposed that there is a large bacterial resistome which is a collection of all resistance genes and their precursors in both pathogenic and non-pathogenic bacteria. Ongoing resistance surveillance programs are also discussed, together with the perspective of a clinical microbiologist. The book then turns to specific themes such as the most serious area of resistance in pathogens, namely in Gram-negative org...
