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This book is a review and description of the state-of-the-art methods of tree-ring analy~is with specific emphasis on applications in the environmental sciences. Traditionally, methods of tree-ring analysis, or more properly in this case methods 0/ dendrochronology, were developed and used for dating archaeological and historical structures and for reconstructing past climates. The classic book Tree Rings and Climate, by H.C. Fritts, published in 1976, provided a superb introduction to the science and an in-depth description of techniques useful for extracting climatic information from tree rings. This book, which was published by Academic Press, is sadly out of print and, even though only 1...
This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.
Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computational methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug Discovery furnishes chemists with the detail they need to identify drug leads with the highest potential before isol...
This study shows that migrant smuggling routes affect every part of the world. It is based on an extensive review of existing data and literature. The study presents detailed information about key smuggling routes, such as the magnitude, the profiles of smugglers and smuggled migrants, the modus operandi of smugglers and the risks that smuggled migrants face. It shows that smugglers use land, air and sea routes - and combinations of those - in their quest to profit from people's desire to improve their lives. Smugglers also expose migrants to a range of risks; violence, theft, exploitation, sexual violence, kidnapping and even death along many routes.
This monograph presents the state of art of the geologic knowledge about the Spanish coast obtained through scientific research in the last 30 years.From a general point of view, coasts are the most quickly changing systems of the Earth. This is critical, since many human resources, such as the main part of economic and social activities, are located in the coastal areas. Especially in the case of Spain these coasts include cities, wide industrial areas (including harbor complexes), important ecologic systems, and our main economic resource: tourism. Understanding the dynamic functioning of each element of this coast is vital for correct future coastal management, so as to solve problems derived from bad plans developed in the last decades of the twentieth century. This is a valuable text for advanced graduate students and coastal researchers, which connects the specific dynamic functioning of the main Spanish coastal environments and their relationships with human activities.
This aim of this open access book is to launch an international, cross-disciplinary conversation on fatherhood engagement. By integrating perspective from three sectors -- Health, Social Policy, and Work in Organizations -- the book offers a novel perspective on the benefits of engaged fatherhood for men, for families, and for gender equality. The chapters are crafted to engaged broad audiences, including policy makers and organizational leaders, healthcare practitioners and fellow scholars, as well as families and their loved ones.
The Agricultural Outlook 2019-2028 is a collaborative effort of the Organisation for Economic Co-operation and Development (OECD) and the Food and Agriculture Organization (FAO) of the United Nations. It brings together the commodity, policy and country expertise of both organisations as well ...