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Os Desafios na Contemporaneidade na Grande Área de Humanas
A ciência moderna é, acima de tudo, uma coerência com o nosso tempo. Ela promove nossas vivências e demonstra o cuidado com a verdade dos fatos, com os estudos das grandes áreas. As ciências humanas nos colocam no patamar do pensamento crítico, capaz de trabalhar questões educacionais como o ensino e aprendizagem e a formação. Esses métodos de conhecimento, em capítulos de livros com artigos científicos, levam ao pensamento crítico de emancipar o homem do conteudismo estrutural, tirando-o da cratera da ignorância e proporcionando fácil acesso ao conhecimento, à ciência e à própria vida. Como dizia Sócrates (470-399 a.C.): "A vida sem ciência é uma espécie de morte". Alessandro Santos.
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Proteomic Methods in Neuropsychiatric Research
Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to cl...
The Role of Cytosolic Sensors in Host Defense to Intracellular Pathogens
Innate immunity is the first arm of the immune system to be triggered in host defense against intracellular pathogens. Some pathogens during evolution have developed stealthy strategies to bypass innate surface receptors but when they reach host cell cytosol they are recognized by cytosolic receptors. Professional phagocytes, such as macrophages, neutrophils, or dendritic cells, have the specialized ability to internalize pathogens into membrane-bound compartments, termed phagosomes. Additionally, pathogen phagocytosis effectively guarantees the concentrated delivery of pathogen-associated molecular patterns (PAMPs) inside cells. Some pathogens can exit phagosomes and survive and replicate i...
Advances in Environmental Accounting & Management
Vol 6 of Advances in Environmental Accounting & Management aims to advance knowledge of the governance and management of corporate environmental impacts and the accounting for these.
