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This book introduces fundamental principles and practical application of techniques used in the scalable production of biopharmaceuticals with animal cell cultures. A broad spectrum of subjects relevant to biologics production and manufacturing are reviewed, including the generation of robust cell lines, a survey of functional genomics for a better understanding of cell lines and processes, as well as advances in regulatory compliant upstream and downstream development. The book is an essential reference for all those interested in translational animal cell-based pharmaceutical biotechnology.
"Buying a house may be love at first sight or seemingly take forever. This terrific book covers all the bases. Readers will enjoy discovering the secrets as they are revealed. There's something valuable for everyone." -Willard Scott, Noted NBC Radio and Television Personality "This book helps you get at not only the practical aspects of home buying and selling, but also the emotional side of what is usually the largest and most anxiety-riddled transactions of your lifetime. If you are thinking of buying or selling a home, it pays big dividends to read Lois Vitt's advice before you do!" -Jordan E. Goodman, America's Money Answers Man and author of Everyone's Money Book "If you want to get in ...
This book introduces readers to the latest findings on disaster robotics. It is based on the ImPACT Tough Robotics Challenge, a national project spearheaded by the Japan Cabinet Office that focuses on developing robotics technologies to aid in disaster response, recovery and preparedness. It presents six subprojects that involve robot platforms and several component technologies used in conjunction with robots: cyber rescue canines, which are digitally empowered rescue dogs; serpent-like robots for searching debris; serpent-like robots for plant/infrastructure inspection; UAVs for gathering information on large areas struck by disaster; legged robots for plant/infrastructure inspection in ri...
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This book offers a timely yet comprehensive snapshot of innovative research and developments in the area of manufacturing. It covers a wide range of manufacturing processes, such as cutting, coatings, and grinding, highlighting the advantages provided by the use of new materials and composites, as well as new methods and technologies. It discusses topics in energy generation and pollution prevention. It shows how computational methods and mathematical models have been applied to solve a number of issues in both theoretical and applied research. Based on selected papers presented at the Grabchenko’s International Conference on Advanced Manufacturing Processes (InterPartner-2019), held in Odessa, Ukraine on September 10-13, 2019, this book offers a timely overview and extensive information on trends and technologies in the area of manufacturing, mechanical and materials engineering. It is also intended to facilitate communication and collaboration between different groups working on similar topics, and to offer a bridge between academic and industrial researchers.
This book is a comprehensive guide to grinding and lapping techniques. It covers everything from basic concepts to advanced tips and tricks, making it an essential resource for professionals and hobbyists alike. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
What if you lived in a world where everybody was kind to each other? What if you were the one who could assist in creating that?What if you had a relationship that was loving, caring, and receiving--and not unaware, not hating, and not judging?Gary Douglas is on a mission to end the perpetual conflict between men and women. Salon des Femmes is based on a series of teleclasses Douglas held with a group of women. They discussed men, sex, relationships, men's and women's roles, and creating amazing, harmonious relationships. It blends the ground-breaking Access Consciousness® tools and processes, insightful revelations and heart-warming inspiration. Says Douglas: "My desire is to give women in...
Mammalian cell lines command an effective monopoly for the production of therapeutic proteins that require post-translational modifications. This unique advantage outweighs the costs associated with mammalian cell culture, which are far grater in terms of development time and manufacturing when compared to microbial culture. The development of cell lines has undergone several advances over the years, essentially to meet the requirement to cut the time and costs associated with using such a complex hosts as production platforms. This book provides a comprehensive guide to the methodology involved in the development of cell lines and the cell engineering approach that can be employed to enhanc...
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