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Effects of Alcohol Use on Immunity and Immune Responses
Alcohol use disorder (AUD) is a significant global health burden. Globally alcohol misuse is the fifth leading risk factor for premature death and disability, and accounts for ~3.3 million deaths annually. Chronic alcohol use deleteriously affects both normal behavior (e.g., depression, anxiety, and alcohol craving) and physiology (e.g., oxidative stress, intestinal hyperpermeability, immune dysfunction, and organ damage). Both heavy and binge drinking patterns alter immune frequencies, compromise immune cell function, resulting in increased morbidity and mortality. Alcohol misuse can damage barrier functions in vital organs such as the lungs, gut, increase susceptibility to both bacterial a...
Microbiome Interplay and Control
In complex systems, such as our body or a plant, the host is living together with thousands of microbes, which support the entire system in function and health. The stability of a microbiome is influenced by environmental changes, introduction of microbes and microbial communities, or other factors. As learned in the past, microbial diversity is the key and low-diverse microbiomes often mirror out-of-control situations or disease. It is now our task to understand the molecular principles behind the complex interaction of microbes in, on and around us in order to optimize and control the function of the microbial community – by changing the environment or the addition of the right microorga...
Choice, Preferences, and Procedures
Kotaro Suzumura is one of the world’s foremost thinkers in social choice theory and welfare economics. Bringing together essays that have become classics in the field, Choice, Preferences, and Procedures examines foundational issues of normative economics and collective decision making. Social choice theory seeks to critically assess and rationally design economic mechanisms for improving human life. An important part of Suzumura’s contribution over the past forty years has entailed fusion of abstract microeconomic ideas with an understanding of real-world economies in a coherent analysis. This volume of selected essays reveals the evolution of Suzumura’s thinking over his career. Grou...
People of the Book
Halbertal provides a panoramic survey of Jewish attitudes toward Scripture, provocatively organized around problems of normative and formative authority, with an emphasis on the changing status and functions of Mishnah, Talmud, and Kabbalah.
The Share Economy
Discussion of profit sharing as a means of combating cyclical unemployment and inflation (stagflation) in market economies - argues that profit sharing will produce full employment without inducing inflation; discusses marginal value economic theory of wages and its effect on the labour market; briefly examines advantages of profit sharing, employee Motivation, etc., and the need for accompanying tax reform. Bibliography.
Inventing the Future
This major new manifesto offers a “clear and compelling vision of a postcapitalist society” and shows how left-wing politics can be rebuilt for the 21st century (Mark Fisher, author of Capitalist Realism) Neoliberalism isn’t working. Austerity is forcing millions into poverty and many more into precarious work, while the left remains trapped in stagnant political practices that offer no respite. Inventing the Future is a bold new manifesto for life after capitalism. Against the confused understanding of our high-tech world by both the right and the left, this book claims that the emancipatory and future-oriented possibilities of our society can be reclaimed. Instead of running from a complex future, Nick Srnicek and Alex Williams demand a postcapitalist economy capable of advancing standards, liberating humanity from work and developing technologies that expand our freedoms. This new edition includes a new chapter where they respond to their various critics.
City on a Hilltop
Since 1967, more than 60,000 Jewish-Americans have settled in the territories captured by the State of Israel during the Six Day War. Comprising 15 percent of the settler population today, these immigrants have established major communities, transformed domestic politics and international relations, and committed shocking acts of terrorism. They demand attention in both Israel and the United States, but little is known about who they are and why they chose to leave America to live at the center of the Israeli-Palestinian conflict. In this deeply researched, engaging work, Sara Yael Hirschhorn unsettles stereotypes, showing that the 1960s generation who moved to the occupied territories were ...
