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Getting into Gypsy Jazz Guitar
This book focuses on the key elements of the Django Reinhardt Gypsy jazz or jazz Manouche guitar style. the information revealed here was gleaned from years of experience jamming with French Gypsies and studying with masters of the style. A native of France, Stephane Wrembel acquired his skills entirely by ear and has taught scores of musicians worldwide using the method that appears here in text and notation for the first time. Written in English, German and French with all musical examples in standard notation and tablature, Wrembel conveys his knowledge in a logical step by step manner, exposing the reader to the authentic Manouche style as it continues to evolve in France and Holland. Medium to advanced in difficulty, this method is designed for the guitarist who is already familiar with jazz harmony and note locations on the fretboard.
NK Cell Subsets in Health and Disease: New Developments
Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.
NK Cell-Based Cancer Immunotherapy
Natural killer (NK) cells are innate lymphoid cells that have a significant role in regulating the defenses against cancer development and certain viral infections. They are equipped with an array of activating and inhibitory receptors that stimulate or diminish NK cell activity, respectively. Inhibitory receptors include, among others, the MHC class I ligands killer cell immunoglobulin-like receptors (KIR) in humans, and members of the Ly49 family of receptors in mice, and CD94/NKG2A. Activating receptors include cytokine and chemokine receptors, and those that interact with ligands expressed on target cells, such as the natural cytotoxicity receptors or NCRs (NKp30, NKp44 and NKp46), NKG2D...
Hematopoietic Cell Transplantation for Malignant Conditions
Get a quick, expert overview of hematologic and non-hematologic malignancies for which hematopoietic cell transplantation is a treatment option. Drs. Qaiser Bashir and Mehdi Hamadani provide easy-to-find information on basic science of hematopoietic cell transplantation, pharmacology, workflows and procedures, possible complications and side effects, in addition to the role of HCT in conjunction with clinical cellular therapy. - Discusses high-dose chemotherapeutic regimens and radiation therapy, patient and donor selection and workup, as well as other key aspects of hematopoietic cell transplantation. - Includes practical information on complications, infectious disease, and special populations such as patients with HIV infection. - Consolidates today's available information in this fast-changing area into one convenient resource.
Evolution of NK-mediated target recognition under the pressure of physiologic or pathologic stimuli
Since their discovery NK cells have come out as potential tools to fight cancer and viruses. This finding early urged different groups to study the mechanisms governing NK cell function. The identification of the MHC-I-specific inhibitory receptors (i.e. KIRs, NKG2A and certain Ly49 molecules) allowed defining rather rapidly how NK cells could avoid self-aggression and how they could be directed towards targets that were forced, by viral infection or tumor transformation, to down-regulate MHC-I expression. In a second time, also the repertoire of surface activating receptors addressing NK cytotoxicity towards tumors and pathogens was mostly defined. In spite of the first findings, however, m...
