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Molecular Biology of Steroid and Nuclear Hormone Receptors
Intracellular Receptors: New Instruments for a Symphony of Signals In the late eighteenth century, it was proposed on theoretical grounds that each of the body's organs, beginning with the brain, must be "a factory and laboratory of a specific humor which it returns to the blood", and that these circulating signals "are indispensable for the life of the whole" (Bordeu 1775). During the nineteenth cen tury, some remarkable physiological experiments revealed the actions of humoral factors that affected the for and function of multiple tissues, organs and organ sys tems within the body (Berthold 1849); much later, the chemical and molecular na ture of some of those factors was determined. Again...
Heat Shock
During the last years the heat shock response has been stu- died as a model system to analyze control mechanisms regula- ting the synthesis of heat shock proteins providing impor- tant general insight into the regulation of gene expression. But the major revelation, which has sparked interest from all quarters of biology, is the discovery that heat shock proteins play major roles in an extraordinary variety of normal cellular processes. They are the focus of investiga- tions in many areas of cell biology, including protein traf- ficking, signal transduction, DNS replication, transcrip- tion, protein synthesis, and in the assembly of di- verse protein structures. These aspects are thoroughly trea- ted in the book, as are the implications in immunology, in- fec- tious diseases, chronic degeneration, hyperthermia, and can- cer research.
Gene Silencing by RNA Interference
Maximizing the potential of RNA interference in functional genomics - as well as in the development of therapeutics - continues to be at the forefront of biomedical research. Unlike journal articles, Gene Silencing by RNA Interference: Technology and Application combines essential background to the RNAi field with practical techniques designed by r
SSC General Awareness Topic-wise LATEST 35 Solved Papers (2010-2016)
Topic-wise Solved Paper SSC General Awareness consists of past solved papers of SSC CGL, 10+2 CHSL, Sub-Inspector, Multi Tasking, and Stenographer from 2010 to 2016. • The coverage of the papers has been kept RECENT (2010 to 2016) as they actually reflect the changed pattern of the SSC exams. Thus the papers prior to 2010 have not been included in the book. • In all there are 35 Question papers from 2010 to 2016 which have been provided topic-wise along with detailed solutions. • Practicing these questions, aspirants will come to know about the pattern and toughness of the questions asked in the examination. In the end, this book will make the aspirants competent enough to crack the uncertainty of success in the Entrance Examination. • The strength of the book lies in the originality of its question papers and Errorless Solutions. The solution of each and every question is provided in detail (step-by-step) so as to provide 100% concept clarity to the students.
Making Sense of Genes
What are genes? What do genes do? These seemingly simple questions are in fact challenging to answer accurately. As a result, there are widespread misunderstandings and over-simplistic answers, which lead to common conceptions widely portrayed in the media, such as the existence of a gene 'for' a particular characteristic or disease. In reality, the DNA we inherit interacts continuously with the environment and functions differently as we age. What our parents hand down to us is just the beginning of our life story. This comprehensive book analyses and explains the gene concept, combining philosophical, historical, psychological and educational perspectives with current research in genetics and genomics. It summarises what we currently know and do not know about genes and the potential impact of genetics on all our lives. Making Sense of Genes is an accessible but rigorous introduction to contemporary genetics concepts for non-experts, undergraduate students, teachers and healthcare professionals.
Railway RRB General Knowledge and General Science Topicwise Previous Question Papers (Bilingual) RRB NTPC, RRB Group D, RPF & Others
Railway RRB General Knowledge and General Science Topicwise Previous Question Papers (Bilingual) RRB NTPC, RRB Group D, RPF & Others
The Molecular Chaperones Interaction Networks in Protein Folding and Degradation
Molecular chaperones are a fundamental group of proteins that have been identified only relatively recently. They are key components of a protein quality machinery in the cell which insures that the folding process of any newly-synthesized polypeptide chain results in the formation of a properly folded protein and that the folded protein is maintained in an active conformation throughout its functional lifetime. Molecular chaperones have been shown to play essential roles in cell viability under both normal and stress conditions. Chaperones can also assist in the unfolding and degradation of misfolded proteins and in disaggregating preformed protein aggregates. Chaperones are also involved i...
Case Studies on Holistic Medical Interventions
The First International Medical Case Reports Conference, 2024(IMED-C) was a pioneering event set to redefine the landscape of medical research and case reporting. This conference was designed to foster collaboration and knowledge exchange among healthcare professionals, researchers, and scholars worldwide. What made this edition exceptional was its virtual online format, breaking down geographical barriers and transforming the way medical knowledge is shared. It was a platform where the latest breakthroughs in medical case reports were unveiled, innovative diagnostic strategies and treatment approaches showcased, and visionary ideas were given a voice. It became a central meeting point for professionals and scholars seeking to share experiences and expertise across borders.
