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Lentiviral Vectors
For the first time a compilation of chapters that depict the biological bases underlying the development of lentiviral vectors, the techniques involved in the manufacture of this new gene delivery tool, and its most promising applications.
Porcine Viruses
This book is a printed edition of the Special Issue "Porcine Viruses" that was published in Viruses
Transacting Functions of Human Retroviruses
The coding domains of simple retrovirus genomes direct the synthesis of virion proteins. Complex retroviral genomes generate in addition to virion proteins regulatory transacting proteins that are translated from multiple spliced messenger RNAs and fulfill important functions in the virus life cycle. All human retroviruses have such complex genomes. The transacting proteins of these pathogens are attractive targets for therapeutic intervention because they are viral specific, are essential for efficient virus replication and may be mediators of viral pathogenicity. In summarizing the current knowledge on the regulatory transacting proteins of human retroviruses this volume makes an important contribution toward the control of virus disease.
iPS Cells for Modelling and Treatment of Human Diseases
This book is a printed edition of the Special Issue "iPS Cells for Modelling and Treatment of Human Diseases" that was published in JCM
Stem Cell Research Progress
There are two broad categories of mammalian stem cells: embryonic stem cells, derived from blastocysts, and adult stem cells, which are found in adult tissues. This text presents research from around the globe in this dynamic field.
Telomerase Inhibition
This volume presents a compendium of the most recent and advanced methods applied to the rapidly expanding field of telomerase inhibition. The techniques described provide the researcher with a diverse and comprehensive set of tools for the study of telomerase inhibition. The volume is aimed at biochemists, molecular biologists, cancer researchers, and geneticists.
Advances in Immunology
Praise for the Series: "The series which all immunologists need." --The Pharmaceutical Journal "Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions." --Science "Deserves a permanent place in biomedical libraries as an aid in research and in teaching." --Journal of Immunological Methods Key Features: * The role of CD40 and its ligand, gp39, as central players in the regulation of B cell growth and differentiation * Prolactin, growth hormone and insulin-like growth factor-I as full-fledged immunological growth and differentiation factors * Transcription factors of functionally mutant mice are highly relevant to understandi...
Handbook of Stem Cell Therapy
The handbook comprehensively reviews the therapeutic potential of stem cells and stem cell secretome-based cell-free strategies in regenerative medicine. The chapters in section I and section II respectively discuss the diverse applications of mesenchymal stem cells and non- mesenchymal stem cells, including skeletal myoblasts, endothelial progenitor cells, adipose tissue-derived stem cells, induced pluripotent stem cells, and neuronal stem cells in myocardial repair, inflammatory bowel disease, cognitive deficits, wound healing, retinal disorders, and COVID-19. The subsequent chapters in section IIIprimarily focused on the fast-emerging cell-free therapy approach in regenerative medicine fo...
Applications of Genome Modulation and Editing
This volume details generation of gene-edited cell lines and organisms as models for human diseases, pest control, and large animal welfare and production outcomes. Chapters guide readers through gene regulation, editing, screening of cell lines, genome editing, and an overview of the tools for efficient genome editing including; ZFNs, TALENs, and CRISPR. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step- by-step, readily reproducible protocols. Authoritative and cutting-edge, Applications of Genome Modulation and Editing aims to be a useful and practical guide for researchers to commence or advance their study in this field.
