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Biogenesis of the oxidative phosphorylation machinery in plants. From gene expression to complex assembly
Mitochondrial biogenesis is an extremely complex process. A hint of this complexity is clearly indicated by the many steps and factors required to assemble the respiratory complexes involved in oxidative phosphorylation. These steps include the expression of genes present in both the nucleus and the organelle, intricate post-transcriptional RNA processing events, the coordinated synthesis, transport and assembly of the different subunits, the synthesis and assembly of co-factors and, finally, the formation of supercomplexes or respirasomes. It can be envisaged, and current knowledge supports this view, that plants have evolved specific mechanisms for the biogenesis of respiratory complexes. ...
Actinobacteria, a Source of Biocatalytic Tools
Actinobacteria (Actinomycetes) represent one of the largest and most diverse phyla among Bacteria. The remarkable diversity is displayed by various lifestyles, distinct morphologies, a wide spectrum of physiological and metabolic activities, as well as genetics. Interestingly, most Actinobacteria have a high GC-content (ranging from 51% to >70%) and belong to Gram-positive or Gram-variable type microbes. Many species are well known for large genomes which may be of linear style as in case of rhodococci or circular. Many of those harbor linear megaplasmids as a kind of genetic storage device. Frequently gene redundancy is reported and in most cases the evolutionary history or a functional rol...
Doing Business in 2004
A co-publication of the World Bank, International Finance Corporation and Oxford University Press
Applied Ontology
Ontology is the philosophical discipline which aims to understand how things in the world are divided into categories and how these categories are related together. This is exactly what information scientists aim for in creating structured, automated representations, called ‘ontologies,’ for managing information in fields such as science, government, industry, and healthcare. Currently, these systems are designed in a variety of different ways, so they cannot share data with one another. They are often idiosyncratically structured, accessible only to those who created them, and unable to serve as inputs for automated reasoning. This volume shows, in a non-technical way and using examples from medicine and biology, how the rigorous application of theories and insights from philosophical ontology can improve the ontologies upon which information management depends.
Comprehensive Foodomics
Comprehensive Foodomics, Three Volume Set offers a definitive collection of over 150 articles that provide researchers with innovative answers to crucial questions relating to food quality, safety and its vital and complex links to our health. Topics covered include transcriptomics, proteomics, metabolomics, genomics, green foodomics, epigenetics and noncoding RNA, food safety, food bioactivity and health, food quality and traceability, data treatment and systems biology. Logically structured into 10 focused sections, each article is authored by world leading scientists who cover the whole breadth of Omics and related technologies, including the latest advances and applications. By bringing ...
The Brain Reward System
This volume explores the latest techniques used to better understand the brain reward system with respect to neurotransmitters, brain structures, and connectivity. This book aims to show readers tested laboratory protocols to study neural circuitry and biological processes implicated in reward, and in neuropsychiatric disorders such as substance use disorders. The chapters are organized into four parts. Part One addresses classical techniques to study the brain reward system, including the curve shift paradigm in intracranial self-stimulation, stereotaxic surgery in rodents, and the use of brain lesions. Part Two focuses on neurochemical, behavioral, and chemogenetic techniques such as immun...
Analytical Chemistry for Cultural Heritage
The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience.Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
