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Mechanism of Muscular Contraction
This book describes the evolution of ideas relating to the mechanism of muscular contraction since the discovery of sliding filaments in 1954. An amazing variety of experimental techniques have been employed to investigate the mechanism of muscular contraction and relaxation. Some background of these various techniques is presented in order to gain a fuller appreciation of their strengths and weaknesses. Controversies in the muscle field are discussed along with some missed opportunities and false trails. The pathway to ATP and the high energy phosphate bond will be discussed, as well as the discovery of myosin, contraction coupling and the emergence of cell and molecular biology in the muscle field. Numerous figures from original papers are also included for readers to see the data that led to important conclusions. This book is published on behalf of the American Physiological Society by Springer. Access to APS books published with Springer is free to APS members.
Liver Myofibroblasts
Myofibroblasts (MFB) are found in most tissues of the body. They have the matrix-producing functions of fibroblasts and contractile properties that are known from smooth muscle cells. Fundamental work of the last decades has shed remarkable light on their origin, biological functions and role in disease. During hepatic injury, they fulfill manifold functions in connective tissue remodeling and wound healing, but overshooting activity of MFB on the other side induces fibrosis and cirrhosis. The present e-book "Liver myofibroblasts" contains 9 articles providing comprehensive information on "hot topics" of MFB. In our opening editorial we provide a short overview of the origin of MFB and their relevance in extracellular matrix formation which is the hallmark of hepatic fibrosis. Thereafter, leading experts in the field share their current perspectives on special topics of (i) MFB in development and disease, ii) their role in hepatic fibrogenesis, and (iii) promising therapies and targets that are suitable to interfere with hepatic fibrosis.
The Journal of Cell Biology
No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-
Molecular Biology of the Cell
MBC online publishes papers that describe and interpret results of original research conserning the molecular aspects of cell structure and function.
Running Science
Running can encompass the absolute extremes of human performance, from speed to endurance. Running Science uncovers the fundamental science that underpins this ubiquitous sport, bringing together the study of biomechanics, nutrition, psychology, health and injury prevention, and the technical development of shoes and running surfaces: it's a complete reference.
Biologie an der Universität Bonn
Als Begriff für eine ›Wissenschaft der belebten Natur‹ wird ›Biologie‹ erstmals um 1800 genutzt. Es ist daher nicht selbstverständlich, dass die Universität Bonn noch in ihrem Gründungsjahr 1818 eine Vorlesung über ›Biologie‹ anbietet. Wolfgang Alt und Klaus Peter Sauer haben nun erstmals eine ausführliche und durchgehend bebilderte Ideengeschichte der biologischen Forschung und Lehre an der Universität Bonn vorgelegt. Von der Zoologie über die Botanik und Genetik bis hin zur Entwicklung der Zellbiologie und Mikrobiologie geben sie Einblicke in die Lokalgeschichte einer sich neu etablierenden und heute zentralen universitären Wissenschaft.
Löffler/Petrides Biochemie und Pathobiochemie
Biochemie in einer neuen Dimension! „Löffler/Petrides Biochemie und Pathobiochemie“ gehört zu den Lehrbüchern, die man unbedingt im Bücherregal haben muss. Ohne ein umfassendes und gleichzeitig verständliches Grundlagenbuch wird man sonst immer Schwierigkeiten haben, die komplexen biochemischen Zusammenhänge so zu verstehen, dass sich dieses Wissen auch in die spätere klinische Tätigkeit transportieren lässt. In der komplett neu konzipierten und überarbeiteten 9. Auflage wurde der Stoff in 74 kleinere Kapitel unterteilt. So fällt zum einen die Orientierung im Inhaltsverzeichnis leichter und zum anderen sind die einzelnen Lerneinheiten deutlich übersichtlicher. Jedes Kapitel i...
