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Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: RNA Viruses, Seventh Edition covers the latest information on RNA viruses, how they cause disease, how they can cause epidemics and pandemics, new therapeutics and vaccine approaches, as provided in new or extensively revised chapters that reflect these advances in this dynamic field. Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases.
When firms need to fill management positions, when experienced managers want a new challenge, or when MBA graduates are looking for their first senior management role, they often turn to headhunters or, more formally, executive search consultants. This guide provides a clear overview of the executive search market, with specific guidelines on using headhunters effectively, both for individuals looking for a job and organizations looking to fill a role. Headhunters offers advice on what’s important in the selection of an executive search firm and provides invaluable networking tips on getting the best search consultants interested in you as a candidate. With the global job market more uncertain than ever, the need for quality career guidance has grown considerably. This new addition to The Economist series helps fill the void for all those looking for a new job—or a new employee.
For a virus to invade a host cell it needs to penetrate the physical barrier imposed by the plasma membrane. Viruses have evolved specialized surface proteins to meet this challenge. These proteins facilitate delivery of the viral genetic information into the host cell by either fusing the viral envelope with a host cell membrane or by forming membrane pores. Membrane fusion and pore formation critically depend on the engagement of host cell receptors and receptor choice is a key determinant of viral tropism. The multi-faceted interplay between viral and cellular factors during virus entry is a fascinating field of study, which can provide important insight into viral pathogenesis and define new targets for intervention. This book provides a comprehensive overview of this exciting field of research.
The aberrant replication pathway of foamy viruses distinguishes them from all other retroviruses. Many details have been accumulated over the past ten or so years. Most of the findings on foamy viruses were obtained by research on a single virus isolate previously called "human foamy virus", which appeared to be the first to be investigated on a molecular level. However, to the editor's knowledge, genuine human foamy viruses do not exist, but several trans-species transmissions of different simian foamy viruses from monkeys and apes to human hosts.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Through an investigation of the nucleocapsid protein of the AIDS virus, this book illustrates how a small disordered basic viral protein controls virus structure, replication and genetic variability. It also highlights novel concepts indicating that proteins devoid of a defined 3D structure can have many different roles as mediated by a series of molecular interactions with RNA molecules, and, as such, behave as molecular adaptors.
Robin W. Winks placed particular emphasis on those developments that most directly explain the nature of the modern world: social diffusion, group and national consciousness, technological change, religious identities-those aspects of intellectual history that have contributed most to our current dilemmas. In turn this means that there is more in World Civilization: A Brief History about nationalism, imperialism, or ethnic identities than there is about monarchies, feudalism, or diplomacy. The result of the strategic and intellectual decisions made with respect to this textbook is that its proportions are not the customary ones. Particular emphasis is placed on the early origins of civilizat...
Alarm im Berliner Regierungsviertel! Der wichtigste Beamte eines Ministers ist verschwunden – er wurde entführt! Der charismatische Wiener André Heidergott ist der Kommissar, dem die Mächtigen Deutschlands vertrauen. Er deckt auf: Das Opfer war ein Meister der Lügen und Intrigen. Ein mächtiger Beamter plötzlich ganz ohnmächtig. Was zieht einen österreichischen Charmeur und Polizeioberkommissar nach Berlin? Natürlich die Liebe! André Heidergott, seines Zeichens leiwander Wiener, wohnt wegen seiner jetzigen Ex-Frau in Moabit. Mit den großen Gefühlen hat sich aber leider auch die gute Laune verflüchtigt. Was auch nicht hilft: Ein hoher Beamter wird entführt – und Heidergott mu...