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This book summarizes and explains the main approaches to age estimation in the living, defining when a parameter may be of use and raising awareness of its limitations. This text ensures that practitioners recognize when an assessment is beyond their area of expertise or beyond verification depending upon the clinical data available. Each key approach to age evaluation has been allotted a single chapter, written by an international leader in the particular field. The book also includes summary chapters that relay readily accessible data for use by the practitioner, and includes important "ageing milestones." This book is indispensable where problems of immigration and legal standing, juvenile vs. adult criminal status, and responsibilities of law enforcement to protect vulnerable persons are key issues on a daily basis. Medical practitioners, forensic practitioners such as pathology, odontology, anthropology and nursing, lawyers, and police would find this book incredibly useful.
This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development – it is a guide, a historical prospective, a practical compendium, and a source of future direction for the field.
Pediatric Neuroophthalmology details the diagnostic criteria, current concepts of pathogenesis, neuroradiological correlates, and clinical management of a large group of neuroophthalmic disorders that present in childhood. Surprisingly distinct from neuroophthalmic disorders afflicting adults, this set of diseases falls between the cracks of most ophthalmology training, and thus, warrants a practical, clinical guide for the practitioner in ophthalmology - the neuroophthalmologist, pediatric ophthalmologist, general ophthalmologist - as well as neurologists and for residents. The authors, leading pediatric ophthalmologists, have taken this difficult subject matter and developed an accessible, user-friendly manual with a detailed approach to the recognition, differential diagnosis, and management of pediatric neuroophthalmologic disorders.
This book gathers outstanding research papers presented at the International Joint Conference on Advances in Computational Intelligence (IJCACI 2020), organized by Daffodil International University (DIU) and Jahangirnagar University (JU) in Bangladesh and South Asian University (SAU) in India. These proceedings present novel contributions in the areas of computational intelligence and offer valuable reference material for advanced research. The topics covered include collective intelligence, soft computing, optimization, cloud computing, machine learning, intelligent software, robotics, data science, data security, big data analytics, and signal and natural language processing.
Cancer has become a leading cause of death and disability and a serious yet unforeseen challenge to health systems in low-and middle-income countries. A protracted and polarized cancer transition is under way and fuels a concentration of preventable risk, illness, suffering, impoverishment from ill health, and death among poor populations. Closing this cancer divide is an equity imperative. The world faces a huge, unperceived cost of failure to take action that requires an immediate and large-scale global response. Closing the Cancer Divide presents strategies for innovation in delivery, pricing, procurement, finance, knowledge-building, and leadership that can be scaled up by applying a dia...
Cytopathology of Infectious Diseases is the first book of its kind to focus entirely on the cytopathology of infectious diseases. It contains all of the pertinent information about the cytology of infectious diseases and microorganisms and will serve as an ideal handy reference. This unique volume covers the cytomorphology of various microorganisms and the host reactions they elicit, and also incorporates an update on advances in the field. Newly recognized infections such as the recent discovery of the Merkel Cell Polyomavirus (MCV) are included, as well as the utility of new immunostains (e.g. CM2B4 for MCV) and the role of molecular techniques that assist in the identification, classifica...
This practical guide is ideal for healthcare professionals, including family medicine and sports medicine physicians, who wish to integrate peripheral joint and soft tissue injection procedures into their practices. Emphasis is placed on helping clinicians perform injections with accuracy and efficiency. Procedures are presented in a step-by-step fashion. A wealth of illustrations adds clarity, and fluoroscopic images are featured where applicable. Billing and coding are covered in order to aid readers in obtaining reimbursement. Chart documentation designed to improve patient management and medical-legal protection is presented via ready-to-use templates that can be inserted into office notes. Key information on needle gauge sizes and medication dosages is summarized in an easily accessible table. A useful discussion on conducting clinical trials is outlined as well.
"Orthodontic Treatment of Class III Malocclusion is a clinical textbook which highlights both research findings as well as clinical treatment of patients with Class III malocclusions. The volume equips readers with a critical review of present information about 1) the craniofacial biology behind various treatment strategies, 2) Diagnosis and treatment planning in both growing and non-growing Class III patients and 3) Contemporary orthodontic appliances using implants and miniscrews. The book is divided into sections proving evidence-based research on the following aspects of Class III malocclusions: the genetic and epigenetic factors contemporary diagnosis and treatment planning for patients...
This comprehensive book grants readers exclusive insight into current advancements in the field of osteoarthritis (OA). Contributions from leading scientists and clinicians provide a detailed introduction into current understanding of the pathogenesis of OA, different joint structures affected by this debilitating disease (hip, knee, elbow, shoulder, foot, ankle, hand, wrist, and spine), current knowledge and practice in imaging, joint conservative strategies, OA biomarkers as well as currently available treatments, their safety profile and future therapeutic targets. This book further discusses the potential of regenerative therapies and recent advances in OA Personalized Medicine, and how collection of OA patient’s phenotypic, genetic and proteomic data is able to direct treatment strategies through Bio-Informatics.