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'Provides comprehensive detail on the various aspects of particular molecules involved in the phases of injury and repair and the cellular movements and processes....This is an excellent reference book for libraries serving biology and health science clientele and for workers in this field of research.' -American Scientist, from a review of the First Edition All chapters of this second edition have been completely revised and expanded-especially the chapters on growth factors and extracellular matrix molecules. New chapters discuss provisional matrix proteins, extracellular matrix receptors, and scarring versus nonscarring wound healing.
Nickeloff (skin cancer research, Cardinal Bernardin Cancer Center, Chicago) and Nestle (cutaneous medicine and immunotherapy, King's College, London School of Medicine at Guy's, UK) assemble 19 review articles on autoimmune disease processes that affect the skin, covering both humoral and cellular immunity. The etiology, cellular and molecular mechanisms, therapeutic strategies, and pathophysiology of diseases such as psoriasis, dermatitis, cutaneous lupus erythematosus, vitiligo, and scleroderma are discussed by individuals in dermatology, genetics, immunology, and pathology who are based around the world. The book is aimed at clinical researchers, students, allergists, immunologists, dermatologists, and internists.
Autoimmune disorders of the skin remain an enigma for many clinicians and scientists not familiar with these mostly severe and chronic diseases. The book provides an overview and the latest information on the broad spectrum of cutaneous autoimmune disorders for clinicians, scientists and practitioners in dermatology, medicine, rheumatology, ENT, pediatrics and ophthalmology. The book is unique since it presents the state-of-the-art knowledge on pathophysiology, clinical diagnosis and management of these disorders provided by the world experts in the field. The primary intention is to broaden the understanding of the pathophysiology of cutaneous autoimmune disorders and to provide a practical guide to how to identify and handle these conditions. The book is illustrated with many tables, illustrative figures and clinical color photographs. The third edition has been thoroughly updated and extended by chapters on paraneoplastic cutaneous syndromes, atopic dermatitis and autoimmunity and Skin manifestations of rheumatic diseases.
Because skin blisters are the initial manifestation of epidermolysis bullosa (EB), patients invariably present to the dermatologist for diagnosis and treatment. However, EB is a systemic disease whose management requires input from clinicians in virtually all fields of medicine, including pediatri cians, surgeons, dentists, gastroenterologists, hematologists, otorhinolaryn gologists, dietitians, and physical therapists, to name a few. Because EB is a rare disease, few clinicians are familiar with it, and many recoil at the pros pect of caring for individuals covered with blisters caused by a disease they know little about. For patients, insult is thus added to injury and they feel abandoned,...
This book focuses on helping both dermatologists and non-dermatologists approach the treatment of each disease in a pragmatic manner. Each chapter reviews the current literature of treatments for each disease, rating disease severity, and provides pragmatic guidelines based on disease severity on the usage of available medications. The current literature does not provide effective guidelines. This book addresses this deficiency. This book will help guide clinicians in implementing appropriate treatments based on the specific disease and its severity, and possible alternatives in an algorithmic format. It will make the management of these diseases more pragmatic based on both the literature and clinical experience of experts.
"This book is excellent in its coverage of neurobiological underpinnings through perception, measurement, and communication...a great resource for researchers and clinicians." Score: 94, 4 stars. --Doody's Medical Reviews "This is an expertly constructed volume, due mainly to an expert composition of authors forthe individual chapters. Every chapter is like opening a door to a different laboratory, eachexamining a unique corner of the tactile research universe."--PsycCRITIQUES "...a solid, authoritative resource."--New Hampshire Nurses Association Touch has received increased attention over the last few decades, with growing recognition of its profound import to all facets of life. The Handb...
This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas am...
This book is the definitive guide to the diagnosis and treatment of various blistering skin diseases. It offers the reader a succinct clinical description for quick recognition of different types of blistering diseases and their relative urgency. It also provides information on the clinical features of blistering skin diseases, differential diagnoses, laboratory findings, and therapeutic strategy. It contains a section on pathogenesis to enhance the readers understanding on the molecular events underlying the blistering disease process. This book is designed for dermatologists in training and in practice, physicians working in emergency departments, candidates for post-registration qualifications, general practitioners and medical students.
Detailing techniques in wound healing and reconstruction, this reference describes the mechanisms and architecture of biological systems to formulate and design natural and synthetic compounds, degradable and non-degradable scaffolds, and targeted drug delivery devices. It offers strategies to control adhesive interactions, elicit specific cellular responses, and improve the biocompatibility, performance, and durability of prosthetic materials. Covering advances in the field, the book discusses the effect of topographical features on cell behaviors such as orientation, adhesion, migration, proliferation, and differentation.