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Published Scientific Papers of the National Institutes of Health
Each issue lists papers published during the preceding year.
Biomedical Advances in Aging
The VIIIth Annual International Spring Symposium on Health Sciences held at the George Washington University School of Medicine in Washington, D.C., attracted over three hun dred fifty scientists from twenty-five countries. The leading scientific experts in the field reported on recent biomedical advances in aging. They provided an up-to-date account of the molecular, genetic, nutritional, and immunological mechanisms associated with the aging process and approaches to intervention and treatment of the major disorders associated with the aging process, including Alzheimer's disease. A unique aspect of this meeting was a concurrent one-day hearing of the U.S. Senate Sub-Committee on Aging, organized by the Alliance for Aging Research. The theme for the hearing was "Advances in Aging Research." Seven scientists attending our aging sym posium were asked to testify. They were Drs. Carl Cotman (University of California-Irvine), Trudy Bush (Johns Hopkins University), Takashi Makinodan (University of California-Los Angeles), William Ershler (University of Wisconsin-Madison), Gino Doria (ENEA, Rome), Mr. Dan Perry (Director of the Alliance for Aging Research), and myself.
Calcium Phosphates in Biological and Industrial Systems
Calcium Phosphates in Biological and Industrial Systems provides a comprehensive discussion on calcium phosphates in the diverse areas of their applications. The authors are all respected specialists in their particular fields, possessing wide knowledge and experience and able to analyze recent results and relate them to their respective areas of expertise. New information, as well as a review of current concepts, highlights the individual contributions. Due to the broad scope of the subject covered and the large number of contributions, this book is divided into three parts. Whilst each section contains a basic theme, there is a considerable overlapping of ideas and approaches. This reflect...
Metal Ions in Biological Systems
This book is wholly devoted to Ca2+ metal ion, as it is so important in regulating a wide variety of biological activities. It deals with calcium and brain proteins, the role of ca2+ in exocytosis, blood coagulation, and the regulation of the skeletal muscle contraction-relaxation cycle.
Amyloidosis
From a process that from the days of Vir chow and Rokitansky, primarily stimulated the relatively narrow interest of pathologists, amyloidosis has risen full-blown as one of the most important of disease complexes. Its presence dominat:es the lesions of Alzheimer's disease, a disease affecting an estimated 2. 5 million people in the U. S. A. and thereby closely rivaling stroke as the third most common cause of death. If, as it has been de scribed, Alzheimer's disease is the "Disease of the Century," then amy loidosis is the Disease Complex of the Ages. It affects in one or more of its manifestations every organ of the body, and is at least as old as the afflicted Egyptian mummies of the pyra...
Calcification in Biological Systems
Calcification in Biological Systems provides a collection of up-to-date papers regarding calcification in a variety of biological systems. The papers are not simple reviews of the literature. Each paper reflects the personal experience of the author(s) and is rich in constructive criticism and suggestions. Topics range from basic molecular processes to general structural problems in systems as different as unicellular organisms and human skeletal tissues. Because calcification is so diffuse in the animal kingdom, this book makes no attempt to achieve a conclusive synthesis of available results and current ideas. Instead, its merit lies in its ability to be useful to investigators with different scientific backgrounds and areas of interest.
