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Aquaporins
This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that a...
Novel Approaches for Bioremediation of Organic Pollution
Proceedings of the 42nd OHOLO Conference held in Eilat, Israel, May 3-7, 1998
Circadian Medicine
Circadian rhythms, the biological oscillations based around our 24-hour clock, have a profound effect on human physiology and healthy cellular function. Circadian Rhythms: Health and Disease is a wide-ranging foundational text that provides students and researchers with valuable information on the molecular and genetic underpinnings of circadian rhythms and looks at the impacts of disruption in our biological clocks in health and disease. Circadian Rhythms opens with chapters that lay the fundamental groundwork on circadian rhythm biology. Section II looks at the impact of circadian rhythms on major organ systems. Section III then turns its focus to the central nervous system. The book then closes with a look at the role of biological rhythms in aging and neurodegeneration. Written in an accessible and informative style, Circadian Rhythms: Health and Disease,will be an invaluable resource and entry point into this fascinating interdisciplinary field that brings together aspects of neuroscience, cell and molecular biology, and physiology.
The Structure of the Ordinary
The influential Dutch architect's long-awaited manifesto on the everyday environment as the first and best ground for establishing the significance and coherence of architecture. According to N. J. Habraken, intimate and unceasing interaction between people and the forms they inhabit uniquely defines built environment. The Structure of the Ordinary, the culmination of decades of environmental observation and design research, is a recognition and analysis of everyday environment as the wellspring of urban design and formal architecture. The author's central argument is that built environment is universally organized by the Orders of Form, Place, and Understanding. These three fundamental, int...
Handbook of Nutrition and Food
The new edition of the Handbook of Nutrition and Food follows the format of the bestselling earlier editions, providing a reference guide for many of the issues on health and well being that are affected by nutrition. Completely revised, the third edition contains 20 new chapters, 50 percent new figures. A comprehensive resource, this book is a reference guide for many of the issues on health and well being that are affected by nutrition. Divided into five parts, the sections cover food, including its composition, constituents, labeling, and analysis; nutrition as a science, covering basic terminology, nutritional biochemistry, nutrition and genetics, food intake regulation, and micronutrients; nutrient needs throughout the human life cycle; assessment of nutrient intake adequacy; and clinical nutrition, from assessments to a wide variety of disease and health topics.
In Medias Res
"Sloterdijk has in recent years grown into one of Germany's most influential thinkers. His work, which is extremely relevant for philosophers, scientists of art and culture, sociologists, political scientists and theologists, is only now gradually being translated in English. This book makes his work accessible to a wider audience by putting it to work in orientation towards current issues. Sloterdijk's philosophy moves from a Heideggerian project to think 'space and time' to a Diogenes-inspired 'kynical' affirmation of the body and a Deleuzian ontology of network-spheres. In a range of accessible and clearly written chapters, this book discusses the many aspects of this thought"--Publisher's website.
Time, Genetics and Complex Disease
Biological traits and diseases tend to be very complex. Time is an aspect that deserves particular attention to study and decipher biological traits and disease mechanisms: many processes including biological rhythms, neurodevelopmental and neurodegenerative mechanisms, and aging have a time-dependent trajectory. Biological rhythms, such as circadian rhythms are a reflection of biological processes over 24 hours. In the case of developmental and aging processes, they reflect biological activities over a much longer time scale, typically across years or even decades. In recent years these research fields have been cross-fertilizing each other. Examples include apparent alterations of circadia...
Neural Regulation of Metabolism
This book systemically describes the mechanisms underlying the neural regulation of metabolism. Metabolic diseases, including obesity and its associated conditions, currently affect more than 500 million people worldwide. Recent research has shown that the neural regulation of metabolism is a central mechanism that controls metabolic status physiologically and pathophysiologically. The book first introduces the latest studies on the neural and cellular mechanisms of hypothalamic neurons, hypothalamic glial cells, neural circuitries, cellular signaling pathways, and synaptic plasticity in the control of appetite, body weight, feeding-related behaviors and metabolic disorders. It then summariz...
