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Glial cells, including microglia, astrocytes, oligodendrocytes, and their progenitors NG2-glia, serve as key players in maintaining structural integrity and complex brain homeostasis. They actively participate in neurotransmission, energy metabolism, synaptic plasticity, neurogenesis, ion balance, immune defense, and the clearance of neuronal debris. However, the physiological functions of glial cells are often compromised in aging, neurodegenerative diseases such as Alzheimer's, Parkinson's, ALS, and multiple sclerosis, as well as in gliomas, brain tumors demanding specialized understanding for effective therapeutic interventions. Physiology and Function of Glial Cells in Health and Disease...
Parkinson’s disease is the second most common neurodegenerative disorder in the world after Alzheimer’s disease. Thanks to the pioneering works of Arvid Carlson in the 20th century identifying dopamine as the main neurochemical agent involved in Parkinson’s disease’s onset and progress, our understanding of the neuropathology has increased. The elaboration of L-Dopa as the first pharmacological treatment approach has brought new hope for curing or at least slowing the neurodegenerative progress and the decline of motor and cognitive functions in Parkinson’s disease patients. To date, imaging techniques along with genetic and biochemical tools have allowed scientists and clinicians ...
According to the World Health Organization (WHO), coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus (SARS-Cov2), which may cause mild to moderate respiratory complications in most infected people. Older people and those with chronic and/or acute illnesses may present serious complications. Underlying mechanisms of the cellular responses to the virus are not fully revealed; therefore, understanding the pathophysiology of COVID-19 is crucial to provide efficient data to define the appropriate and effective therapeutic strategies to cure and prevent COVID-19-associated complications. The Handbook of Research on Pathophysiology and Strategies for th...
The faster climate change affects the globe, the faster individuals will see the negative consequences, which include the decline of general human health. Comprehension of all climate change-related etiologies is essential to understanding the importance of global environmental stability. The Handbook of Research on Global Environmental Changes and Human Health is a collection of innovative research to manage the ensuing and numerous climate and anthropogenic threats to human health. While highlighting topics including government policy, human security, and population sensitivity, this book is ideally designed for environmentalists, policymakers, sociologists, physio pathologists, epidemiologists, and students seeking current research on reducing population sensitivity in terms of health related to the different climatic risks in the changing world.
Climate change is an issue that has been generating a significant amount of discussion, research, and debate in recent years. Climate change continues to evolve at a rapid rate and continues to have a wide array of effects on everything from temperature to plant life. Beyond the negative environmental impacts, climate change is also proving to be a detriment to society with increasingly violent natural disasters and human health effects. It is essential to stay up to date on the latest in emerging research within this field as it continues to develop. The Research Anthology on Environmental and Societal Impacts of Climate Change discusses the varied effects of climate change throughout all a...
This book brings together innovative research that examines respectively climate change, agricultural production, environmental impacts, food security, nutrition and human health issues with regard to international policies as well as sustainable development goals. As sustainability continues to be a high concern in the scholarly community, food security has become a critical worldwide topic. Food supplies are challenged by factors such as toxicity, substandard food processes, difficulties in providing food to struggling populations and changes to the environment due to climate change egislation can protect public health, but law-makers must understand the current complications facing food security today. This book features a broad range of topics including ecotoxicology, smart food, and wastewater reuse impacts. The book aims to look at how we can protect and improve the health of vulnerable populations as well as innovative solutions to food insecurity. It is ideally designed for university students, from undergraduate to Ph.D. level, professors, researchers, professionals, environmentalists, physio-pathologists, medical doctors, epidemiologists, policies makers and sociologists.
Reproductive health and rights are critical topics in today’s society as laws and policies are continuously debated and adjusted across the world. There are many different outlooks on these issues, and different countries have widely varying laws in place at present. In order to better understand where the world currently is regarding these pressing discussions, further study is needed on the status of women’s reproductive rights. The Research Anthology on Advancements in Women's Health and Reproductive Rights provides a thorough review of the current research available regarding reproductive health. The book discusses how various countries and regions are handling reproductive rights as well as current issues women face within their reproductive health journeys. Covering topics such as sexual health, gender, and pregnancy, this major reference work is ideal for nurses, government officials, policymakers, healthcare professionals, researchers, scholars, academicians, practitioners, instructors, and students.
Cognitive impairment, through Alzheimer’s disease or other related forms of dementia, is a serious concern for afflicted individuals and their caregivers. Understanding patients’ mental states and combatting social stigmas are important considerations in caring for cognitively impaired individuals. Technology is playing an increasing role in the lives of the elderly. One of the most prevalent developments for the aging population is the use of technological innovations for intervention and treatment of individuals with mental impairments. Research Anthology on Diagnosing and Treating Neurocognitive Disorders examines the treatment, diagnosis, prevention, and therapeutic and technological...