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Vascular Aging: Facts and Factors
The increasing mean age of the population in developed countries has turned out to be an economic and social problem. Cardiovascular disease has long been considered to be age related in terms of their onset and progression. As such, we can say that the increase in life expectancy goes in parallel with increased incidence of cardiovascular disease. With age, a number of changes occur in the vasculature altering the homeostasis of the irrigated organs promoting target organ damage. While different adaptive mechanisms to protect vessels against mild stress have been described, the aging process induces a progressive failure of protective mechanisms, leading to vascular changes and higher susce...
The CHILDES Project: The database
"The CD-Rom includes the transcript files described in volume II"--Page 4 of cover.
Experimental Headache Models
Contains papers from the November 1994 Fifth International Headache Research Seminar in Copenhagen, Denmark, plus summaries of articles, in sections on the general use of models in drug development; models currently in use at the preclinical level in migraine research; the use of animal experiments to study the neurobiological basis for pain; the molecular biology of the 5-HT(1D) receptor system; in vivo models; headache models in humans following nitroglycerin or histamine administration; and nonmigrainous headaches. Annotation copyright by Book News, Inc., Portland, OR
The Grammar of the Utterance
This book examines how speakers of Ibero-Romance 'do things' with conversational units of language, paying particular attention to what they do with i) vocatives, interjections, and particles; and ii) illocutionary complementizers, items that look like subordinators but behave differently. Alice Corr argues that the behaviour of these conversation-oriented items provides insight into how language-as-grammar builds the universe of discourse. The approach identifies the underlying unity in how different Ibero-Romance languages, alongside their Romance cousins and Latin ancestors, use grammar to refer - i.e. to connect our inner world to the one outside - and the empirical arguments are underpi...
The Adrenergic Receptors
An authoritative review of the current state-of-the-art understanding of the structure and function of the adrenergic receptor subtypes, as well as of the role played by these receptors in physiological and pathophysiological settings. Topics range from structure-function studies and the imaging of adrenergic receptors to the use of genetically altered mouse models and pharmacogenomics. Highlights include a survey of the knockout and overexpressed mouse models, a review of the new ways that adrenergic receptors can signal, and the effects of polymorphisms on clinical outcomes and on potential gene therapy applications. The side-by-side comparison of all the adrenergic receptors (a1, a2, and b) provides the reader with an excellent survey of the field, including the rationale for designing better drugs to control blood pressure and heart function.
Rista
År 1951. I ett lönnfack har Elin Roth gömt Sändebudets meddelande om ett mystiskt dödsfall i västra Värmland. Elin har lovat sig själv att låta brottsutredningarna vara efter ett tragiskt dödsfall inom familjen, men flera krafter får henne att lämna hemstaden Filipstad för att ta sig an fallet som väntar i byn Glava. Elin förstår omgående att ingen tror att ett brott har begåtts, men efterforskningar visar att det hela började redan på 1920-talet – och att fler liv står på spel. Samtidigt som Elin utreder de mystiska dödsfallen i Glava undersöker hon sitt eget förflutna då det är något som gäckar henne. Snart inser hon att dörren hon har öppnat borde ha förblivit stängd. Rista är tredje delen i den värmländska författaren Helén Wighs trolska spänningsserie om Elin Roth, en ung kvinna som gräver i ouppklarade dödsfall på egen hand i en tid som inte låter henne göra verklighet av sina polisdrömmar.
Complèxica. Cervell, societat i llengua des de la transdisciplinarietat
El triangle llengua-comunicació-societat emmarca els fenòmens més característics del pla sociohumà i, per avançar en el coneixement del seu funcionament, cal desafiar les aproximacions tradicionals i les més formalitzadores a favor d’enfocaments complèxics, transdisciplinaris i qualitatius integrats. Atesa la gran diversitat cognitiva i cultural dels humans, com també de les seves especificitats emocionals i comportamentals, tenim el repte d’intentar construir un cos teòric i metodològic adequat a les propietats característiques dels fenòmens humans per avançar cap a una sociocomplexitat cognitivoemotiva. Aquest volum vol posar en relació el cervell, la societat i la llengua, tres sistemes complexos adaptatius íntimament imbricats que són a la base de la comunicació humana. La principal aportació de l’obra rau en el fet que els autors aborden diverses temàtiques des d’una visió holística i complèxica emfasitzant les interrelacions i els fenòmens emergents.
Parliamentary Diplomacy in European and Global Governance
In Parliamentary Diplomacy in European and Global Governance, 27 experts from all over the world analyse the fast-expanding phenomenon of parliamentary diplomacy. Through a wealth of empirical case studies, the book demonstrates that parliamentarians and parliamentary assemblies have an increasingly important international role. The volume begins with parliamentary diplomacy in Europe, because the European Parliament is one of the strongest autonomous institutional actors in world politics. The study then examines parliamentary diplomacy in relations between Europe and third countries or regions (Mexico, Turkey, Russia, the Mediterranean), before turning attention to the rest of the world: North and South America, Asia, Africa and Australia. This pioneering volume confirms the worldwide nature and salience of parliamentary diplomacy in contemporary global politics.
Farmacología ocular
Farmacología ocular alcanza su segunda edición con el deseo de colaborar en el desarrollo de una disciplina que ha experimentado un notable avance en los últimos años. En la presente obra se revisan los principios básicos de la farmacología que permiten comprender cómo los medicamentos ejercen sus acciones, así como los efectos terapéuticos e indeseables derivados de éstas. También se analizan, de forma detallada, las propiedades de algunos grupos farmacológicos que son de uso frecuente por los profesionales dedicados al cuidado de la función ocular pero difíciles de encontrar en las obras de farmacología o de óptica. Farmacología ocular ofrece los conocimientos esenciales que precisan aquellos lectores que van a ejercer o ejercen su actividad profesional en el ámbito de la óptica y la optometría.
