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Clinical Management of Acute Lymphoblastic Leukemia
This book provides a state-of-the-art overview of acute lymphoblastic leukemia (ALL). The first section of the book presents the translational science behind ALL, reviewing molecular pathways and targets in B- and T-cell ALL, as well as techniques and application of minimal residual disease testing. The second section spotlights ALL management strategies for patients across the spectrum, from infants to the elderly. The final section outlines current and new advances in ALL treatment, including new monoclonal antibodies and allogenic and autologous HSCT. Written by experts in the field, Clinical Management of Acute Lymphoblastic Leukemia: From Bench to Bedside is a valuable resource that will guide patient management, stimulate investigative efforts, and increase understanding of the biologic underpinnings of the disease.
Cancer in Children and Adolescents
Edited by two leading childhood cancer specialists, and with contributions from authoritative experts in the field, this comprehensive reference covers all aspects of major childhood cancers including molecular oncology and translational therapy, pathological evaluation of childhood cancer, surgical management of pediatric tumors, non-hodgkin's lymphoma and lymphoproliferative disorders in children, infant brain tumors, prevention, diagnosis and treatment of infectious complications, pain management, late effects of childhood cancer therapy.
Childhood Leukemia
This book is a comprehensive and up-to-date compendium on all aspects of childhood leukemia. After introductory chapters on the epidemiology and biology of pediatric leukemia, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. Promising targeted agents are discussed, and strategies for the development of new agents are appraised. The late effects of leukemia and its therapy are then considered in depth, with due attention to management of the psychosocial impact of the disease. Finally, global strategies to improve leukemia care and outcome are reviewed, and future directions discussed. The authors are internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric leukemia and will prove invaluable to specialists, generalists, and trainees alike.
Hematopoietic Cell Transplantation in Children with Cancer
This book is a comprehensive and up-to-date compendium on all aspects of blood and marrow transplantation in children. After an introductory chapter describing the history of pediatric blood and marrow transplantation, subsequent chapters discuss pediatric-specific aspects of transplantation, including stem cell sources suitable for transplantation, preparative regimens, graft-versus-host disease, complications related to transplantation, and late effects. The role of blood and marrow transplantation in various specific pediatric diseases is then examined, and the closing chapter considers future directions. The authors are all internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric diseases that are treatable with blood and marrow transplantation and will prove invaluable to specialists, generalists, and trainees alike.
Beautiful Monster
A breathtaking, exquisitely crafted memoir about a trans person’s singular journey through breaching the boundaries of gender—across generations, cultures and borders—to become his truest, most authentic self. Nearing the age of forty, with an entire life already lived as a woman—half in Colombia, half in the US—Miles Borrero comes face to face with his father’s impending death. Suddenly realizing that he has been stalling his transition for fear of losing his family’s love, this moment catalyzes Miles’s determination to be fully known as his father’s son before it is too late. In Beautiful Monster, Miles chronicles his unusual childhood, by turns riveting and hilarious, in...
Molecularly Targeted Therapy for Childhood Cancer
Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular ‘drivers’ can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered. This volume will provide a comprehensive summary of molecular characteristics of childhood cancers, and how the changes involved in transformation provide us with opportunities for developing relatively less toxic, but curative, therapies.
The White, Hill, Wiley, & Kuns Cousins
John White (d.1787/1788) was a son of Conyers and Mary White of Leicestershire, England. He married Ann Wisdom, and about 1738 they immigrated to Orange (later Greene) County, Virginia. Descendants and relatives lived in Virginia, Pennsylvania, New York, Ohio, Missouri, Iowa, Nebraska, Wyoming, California and elsewhere.
Holland-Frei Cancer Medicine
Die neueste Ausgabe des Goldstandards in der Krebsforschung und klinischen Onkologie Mit der neu überarbeiteten zehnten Ausgabe von Holland-Frei Cancer Medicine legt ein Team anerkannter Forscher und Ärzte einen umfassenden aktuellen Überblick über die Krebsforschung und die klinische onkologische Praxis vor. Das Werk enthält zeitgemäße und unverzichtbare Informationen aus den Bereichen Epidemiologie, Ätiologie, Krebsbiologie, Immunologie, Prävention, Screening, klinisches Erscheinungsbild, Pathologie, Bildgebung und Therapie. Ausgehend von einem grundlegenden Verständnis der Krebsbiologie stellt Holland-Frei Cancer Medicine eine Verbindung zwischen wissenschaftlichen Prinzipien un...
