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Multiple Myeloma
Multiple myeloma is currently still an incurable disease, but during the past decade knowledge of its molecular pathogenesis has increased rapidly. This has led to remarkable progress in both diagnosis and therapy, including in particular the approval of novel and first-in-class drugs such as thalidomide, bortezomib, and lenalidomide. This book, written by internationally acknowledged experts, covers a wide range of topics relating to multiple myeloma, including history, epidemiology, pathophysiology, clinical features, staging, and prognostic systems. The principal focus, however, is on therapy, with detailed information on the various promising treatment options which give hope that this cancer will be transformed into a chronic disease or even become curable. Individualized therapy and the variety of supportive treatment options, as described in this volume, will help in achieving this goal, as well as in reducing adverse events and improving quality of life.
The Allotment Movement in England, 1793-1873
The living standards of the rural poor suffered a severe decline in the first half of the nineteenth century as a result of high population growth, changing agricultural practices, enclosure and the decline of rural industries. Allotment provision was the most important counterweight to the pressures. This book offers the first systematic analysis of the early nineteenth-century allotment movement, providing new data on the chronology of the movement and on the number, geographical distribution, size, rents, cultivation yields and effect on living standards of allotments, showing how the movement brought the culture of the rural labouring poor more closely into line with the mainstream values of respectable mid-Victorian England. This book casts new light on central aspects of early and mid-nineteenth-century social and economic history, agriculture and rural society. JEREMY BURCHARDT is lecturer in Rural History, University of Reading.
