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Environmental Protection Against Radioactive Pollution
NATO Advanced Research Workshop "Environmental Protection Against Radioactive Pollution" was held in Almaty on September 16-19, 2002. Experts from Azerbaijan, Denmark, Hungary, Kazakhstan, Kyrgyzstan, Norway, Russia, Tajikistan, Turkey, Ukraine, USA, Uzbekistan and the IAEA have participated and made presentations. The Workshop was organized parallel to the “2nd Eurasia Conference on Nuclear Science and its Application” held in Almaty on September 16-19, 2002 that was organized by Institute of Nuclear Physics of Kazakhstan with Turkish Atomic Energy Authority and National Academy of Science of Azerbaijan, National Academy of Science of Kyrgyzstan, Institute of Nuclear Physics of Uzbekist...
Radiation Therapy Using MRI-LINAC - the Right Way to Start: a Guide for Physicians and Physicists, volume II
MRI-LINAC based radiation treatments are currently being used for selected patient populations and body regions, and knowledge related to the outcomes of this modality is progressing. The outcome and long-term side effects in comparison with other modern LINAC are now being studied. As contouring, planning, quality assessment, and treatment assessment require new techniques for the use of all team members, including technicians, dosimetrists, and physicians, research reporting on these factors and each stage of the process is needed for medical professionals. Furthermore, as physicians report a low incidence of acute side effects, with almost none for long-term follow-up, this knowledge should be published in the radiation milieu. The goal of this Research Topic is to collect and summarise the growing knowledge from institutions using MRI-LINAC, in order to share the obstacles, solutions, learning curves, and innovations of this new treatment modality.
Nasopharyngeal Cancer
Nasopharyngeal Cancer - Multidisciplinary Management provides a comprehensive account of the current state of knowledge on nasopharyngeal cancer and its multidisciplinary management. The first ten chapters document contain essential background information on subjects such as epidemiology, pathogenesis, molecular biology, pathology, and the use of imaging in diagnosis and staging. Subsequently, the various treatment options and combinations in a range of settings are examined in depth. Detailed attention is given to the roles of concurrent, adjuvant, and neoadjuvant chemotherapy and advanced radiotherapy techniques. Further chapters then explore surgical treatment, follow-up, treatment of metastatic disease, treatment-related complications, and nasopharyngeal cancer in children. This is an important book that will prove essential reading for the radiation oncology community worldwide and meet the need for substantial improvements in knowledge of modern techniques.
Imaging Neuroinflammation
Imaging Neuroinflammation provides an overview of the molecular and cellular basis of inflammation and its effects on neuroanatomy, reviews state-of-the-art imaging tools available to measure neuroinflammation, and describes the application of those tools to both preclinical animal disease models and human disease.This book is an authoritative reference on imaging neuroinflammation, MRI, neuroinflammation, MR Spectroscopy of inflammation, Iron imaging in inflammation, and more. - Explains how inflammation in the central nervous system impacts tissue microstructure - Presents imaging methods that are useful for assessing neuroinflammation - Describes preclinical models of neuroinflammation - Reviews the role of neuroinflammation in human injury and disease states
Nasopharyngeal Cancer
This book provides up-to-date guidance that will assist radiation oncologists during the day-to-day management of nasopharyngeal cancer. After discussion of diagnosis and staging, target delineation techniques and treatment planning are described for both intensity-modulated and particle radiation therapy. Detailed information is then presented on the application of radiation therapy in different disease settings, from early stage disease to metastatic disease. Due attention is paid to the role of multimodality treatment and new and advanced technologies in particular circumstances, such as local recurrence. In addition, follow-up and the management of late toxicities are explained and management strategies are documented for special situations and groups, including pediatric patients. The book is published within the Springer series Practical Guides in Radiation Oncology. Like other volumes in the series, it is designed for hands-on use by both radiation oncology residents and practicing radiation oncologists. It will also be of value for head and neck physicians.
Abuse of Minors in Clinical Studies
With the emergence of effective drugs and observed drug toxicities in babies, two mantras emerged: that children are therapeutic orphans, and that children are not small adults. US and EU laws demand pediatric studies as a condition for the approval of new drugs in adults. This is called “Pediatric Drug Development” (PDD). Although apparently reasonable, there are catches. Children are vulnerable at birth, but they grow and become bodily mature with puberty, well before coming of age. Minors are not another species. The 18th birthday, an administrative/ legal limit, does not correspond to a physiological change. Drugs treat the body, not the legal status. PDD results in pointless studies in bodily mature adolescents, and in exaggerated studies in younger minors. An originally well-intentioned concept results in thousands of questionable studies worldwide. This book draws attention to conflicts of interest and ethical dilemmas of PDD and questions its applicability for adolescents and minors that are no longer babies.
Ultra-High Field Neuro MRI
Ultra-High Field Neuro MRI is a comprehensive reference and educational resource on the current state of neuroimaging at ultra-high field (UHF), with an emphasis on 7T. Sections cover the MR physics aspects of UHF, including the technical challenges and practical solutions that have enabled the rapid growth of 7T MRI. Individual chapters are dedicated to the different techniques that most strongly benefit from UHF, as well as chapters with a focus on different application areas in anatomical, functional and metabolic imaging. Finally, several chapters highlight the neurological and psychiatric applications for which 7T has shown benefits. The book is aimed at scientists who develop MR techno...
MR Linac Radiotherapy
MR Linac Radiotherapy: A New Personalized Treatment Approach comprises both clinical and physical aspects of this new technology. The book covers treatment planning, workflow and technical issues about MR-Linac. Specially, the clinical use of MR-Linac according to different cancer types is presented by experienced physicians. This is a unique guide for medical physicists, RTTs, dosimetrists and physicians, as well as radiation oncologists and their teams. The MR Linac combines two technologies - a magnetic resonance imaging scanner and a linear accelerator - to precisely locate tumors, tailor the shape of radiation beams in real-time, and precisely deliver doses of radiation, even to moving tumors. This highly innovative technology is very new, and the number of newly installed MR-Linac machines will gradually increase worldwide. However, as there is no published book as a guideline, this book will help new MR-Linac users and centers planning to have MR-Linac. - Presents the first book on MR Linac Radiotherapy - Comprises both clinical and physical aspects of this new technology - Written by leading editors and authors in the field
Quantitative Perfusion MRI
Quantitative Perfusion MRI: Techniques, Applications, and Practical Considerations, Volume 11 clearly and carefully explains the basic theory and MRI techniques for quantifying perfusion non-invasively in deep tissue, covering all aspects of perfusion imaging, from acquisition requirements to selection of contrast agents and appropriate pharmacokinetic models and for reliable quantification in different diseases and tissue types. Specifically, this book enables the reader to understand what microvascular functional parameters can be measured with perfusion MRI, learn the basic techniques to measure perfusion in different organs, apply the appropriate perfusion MRI technique to the organ of i...
