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Antiepileptic Drugs
The thoroughly revised, updated Fifth Edition of this classic is the m ost comprehensive, current, and authoritative reference on all anticon vulsants available today. This edition features detailed profiles of n ewer drugs--including levetiracetam, oxcarbazepine, tiagabine, topiram ate, and zonisamide--and new chapters on use of antiepileptic drugs in children and during pregnancy. Drugs are covered in alphabetical ord er and in an easy-to-follow format: mechanisms of action; chemistry, b iotransformation, and pharmacokinetics; interactions; clinical efficac y and use; and adverse effects. Coverage of clinical use includes none pileptic and psychiatric disorders where appropriate. This edition has been trimmed to manageable size by shortening chapters on older, less frequently used drugs.
The Right Therapy for Neurological Disorders
Most neurological disorders are chronic and aging-related. With the increase of life expectancy their incidence and prevalence will grow in the decades to come, which in turn will increase the load on medical and social systems worldwide. There is thus a desperate need for successful preventive and therapeutic measures based on randomized clinical trials (RTCs) conducted by independent organizations. This book provides a compendium relating most of the principles of reliable RTCs to specific neurological diseases. Contributed by specialized neurologists, the articles touch on important aspects of RCTs with a clear critical approach, highlighting their limitations as well as giving recommendations for their planning and conducting to address the variable genotypic and phenotypic aspects of neurological conditions. Consideration is also given to combining the clinical impact of the study results with patients’ values and the interests of pharmaceutical companies. Neurologists involved in clinical trials will certainly benefit from this book, which should become a basic text for all neurological courses dealing with evidence-based neurology.
Neuropsychiatric Symptoms of Epilepsy
This book is an up-to-date, comprehensive review of the neuropsychiatry of epilepsy, by active authorities in the field, with an emphasis on clinical and management issues. A critical appraisal of the methodology and limitations of current research on the neuropsychiatry of epilepsy is provided, and unanswered questions and controversies are addressed. Pharmacological aspects of management are also discussed in order to enable the reader to manage these patients more safely. Neuropsychiatric Symptoms of Epilepsy is aimed at neurologists, epileptologists, psychiatrists and neuropsychiatrists, and will also be of interest to psychologists and neuropsychologists, research and specialist nurses, clinical researchers and methodologists.
From First Unprovoked Seizure to Newly Diagnosted Epilepsy
This new edition of the book series dedicated to “Progress in Epileptic Disorders” is the result of a recently held unique gathering of international experts that debated on the prognostic and therapeutic issues raised by the management of first unprovoked seizures and of newly diagnosed epilepsy. Current knowledge on natural evolution of a first seizure, the role of co-morbid conditions, the impact of immediate versus delayed treatment and recent guidelines are thoroughly addressed. The new ideas and suggestions that emerge from this book offer challenging perspectives for both patient care and clinical as well as fundamental research. The first section of the book includes an up to dat...
Long-Term Outcomes of Epilepsy Surgery in Adults and Children
This book provides a comprehensive, rigorous review of the long-term outcome literature in epilepsy surgery in both adults and children. Each chapter examines the long-term outcome literature in a separate domain; covering seizure control, social, vocational/educational and psychiatric outcomes. Behavior and cognition are also discussed. The clinical predictors of good and bad outcomes in each domain are described and the gaps in current knowledge are highlighted. Separate chapters examine the methodological challenges associated with long-term outcome studies and the special considerations associated with informed consent in this population. Long-Term Outcomes of Epilepsy Surgery in Adults and Children is essential reading for all members of multidisciplinary epilepsy surgery teams, including neurosurgeons, neurologists and neuropsychologists; it will enable these teams to counsel patients and parents who are considering epilepsy surgery as a therapeutic option.
Epilepsy Research Progress
Epilepsy, also called seizure disorder, is a condition of the brain marked by a susceptibility to recurrent seizures. Epilepsy affects 1 per cent to 2 per cent of the population. In about half the cases of epilepsy, the cause is unknown. However, some possible causes of epilepsy include: birth trauma, perinatal infection, anoxia, infectious diseases, ingestion of toxins, tumours of the brain, inherited disorders or degenerative disease, head injury or trauma, metabolic disorders, cerebrovascular accident and alcohol withdrawal. This new book presents the latest worldwide research in this field.
Prognosis of Epilepsies
The last book on the prognosis of epilepsies was written by Rodin in 1968. For the next 35 years, many original papers or chapters in textbooks were published on this complex topic. Most of these endeavours, reflecting the clinician's highly detailed point of view were based on selected cases with little concern for the epidemiological context or upon the epidemiologist's population-based approach which tends to ignore important clinical details. Until quite recently, fundamental epidemiological aspects of epilepsy, as it is understood by clinicians, have not been explored, and clinicians viewed populationbased epidemiology as relatively irrelevant to their daily practice. This book is divided into two majors parts. Presentations in the first part address methodological issues regarding prognostic studies (including remission and mortality) as well as results from long-term cohort studies. The second part contains presentations on the clinical aspects and prognosis of several individual epilepsy syndromes as well as presentations about the prognosis of status epilepticus and outcome of frontal and temporal lobe surgery.
Investigating Neurological Disease
This invaluable handbook for clinicians reviews the epidemiology, treatment and prognosis of all major diseases of the nervous system.
Handbook of Clinical Neuroepidemiology
In recent years there have been significant advances in the knowledge of risk factors, gene-environment interactions, incidence, prevalence, outcomes, and prevention strategies of many neurological disorders. These advances have been accompanied by developments in study design methodologies and statistical analysis. This handbook bridges the gap between current neuroepidemiological knowledge and its evidence-based application in everyday practice.
Epilepsy: A Comprehensive Textbook
Authoritative and updated, Epilepsy: A Comprehensive Textbook, 3rd Edition, contains 365 chapters that cover the full spectrum of relevant topics in biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Written by world-renowned authorities and expertly edited by epileptologists Drs. Jerome Engel, Jr., Solomon L. Moshé, Aristea S. Galanopoulou, John M. Stern, Alexis Arzimanoglou, Jacqueline A. French, Renzo Guerrini, Andres M. Kanner, and Istvan Mody, this three-volume work includes detailed discussions of seizure types and epilepsy syndromes, relationships between physiology and clinical events, psychiatric and medical comorbidities, conditions that could be mistaken for epilepsy, and an increasing range of pharmacologic, surgical, and alternative therapies.
