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The most comprehensive and integrated book on pigmentation The Pigmentary System, Second Edition, gathers into one convenient, all-inclusive volume a wealth of information about the science of pigmentation and all the common and rare clinical disorders that affect skin color. The two parts, physiology (science) and pathophysiology (clinical disorders), are complementary and annotated so that those reading one part can easily refer to relevant sections in the other. For the clinician interested in common or rare pigment disorders or the principles of teaching about such disorders, this book provides an immediate and complete resource on the biologic bases for these disorders. For the scientis...
Over the past three decades, the exploding number of new technologies and applications introduced in medical practice, often powered by advances in biosignal processing and biomedical imaging, created an amazing account of new possibilities for diagnosis and therapy, but also raised major questions of appropriateness and safety. The accelerated development in this field, alongside with the promotion of electronic health care solutions, is often on the basis of an uncontrolled diffusion and use of medical technology. The emergence and use of medical devices is multiplied rapidly and today there exist more than one million different products available on the world market. Despite the fact that the rising cost of health care, partly resulting from the new emerging technological applications, forms the most serious and urgent problem for many governments today, another important concern is that of patient safety and user protection, issues that should never be compromised and expelled from the Biomedical Engineering research practice agenda.
This two-volume set is a complete guide to the diagnosis and management of ophthalmic diseases and disorders. Volume One begins with an overview of basic sciences, ocular pathology, and clinical examination. The remainder of this volume and Volume Two discuss numerous diseases that may occur in different parts of the eye. The second edition has been fully revised and features many new topics including innovative techniques in cataract surgery, imaging modalities, pharmacotherapy, new surgical procedures, and much more. This comprehensive text is highly illustrated with nearly 1900 clinical photographs, radiological images, diagrams, tables and boxes. Key points Two-volume guide to diagnosis and management of ophthalmic disorders and diseases Fully revised, second edition with many new topics Highly illustrated with nearly 1900 photographs, diagrams and tables Previous edition (Vol 1 9780721672113 and Vol 2 9780721672120) published in 1980
Photodynamic therapy (PDT) utilizes photosensitizers (PS) together with irradiating light of specific wavelength interacting with oxygen to generate cytotoxic reactive oxygen species, in particular singlet oxygen, which has been approved for the clinical treatments of several malignant and non-malignant pathologies. Most recently, enhanced PDT was successfully achieved by using new light sources (i.e., light-emitting diode), novel functional nano-PSs, oxygen supply and synergistic therapy. In addition, PDT was widely used in the fields of antibacterial, antimicrobial and antibiofilm activities. The aim of this book is to highlight innovations in the fundamental mechanisms of enhanced PDT for clinical applications, and 20 papers published in the Journal of Innovative Optical Health Sciences during 2020-2023 were selected.
This book covers different aspects of bioinorganic chemistry with in-depth and up-to-date coverage. Topics include photosynthesis, nitric oxide complexes and their therapeutic aspects in human beings and plants, carbon monoxide complexes and their therapeutic aspects in human beings and plants, and gaseous signaling molecule hydrogen sulfide and their donors in ophthalmic diseases and physiological implications in plants.
This book gathers outstanding papers presented at the European Conference on Numerical Mathematics and Advanced Applications (ENUMATH 2019). The conference was organized by Delft University of Technology and was held in Egmond aan Zee, the Netherlands, from September 30 to October 4, 2019. Leading experts in the field presented the latest results and ideas regarding the design, implementation and analysis of numerical algorithms, as well as their applications to relevant societal problems. ENUMATH is a series of conferences held every two years to provide a forum for discussing basic aspects and new trends in numerical mathematics and scientific and industrial applications, all examined at the highest level of international expertise. The first ENUMATH was held in Paris in 1995, with successive installments at various sites across Europe, including Heidelberg (1997), Jyvaskyla (1999), lschia Porto (2001), Prague (2003), Santiago de Compostela (2005), Graz (2007), Uppsala (2009), Leicester (2011), Lausanne (2013), Ankara (2015) and Bergen (2017).
Numerous scholarly articles and books have been written about biologic and social evolution, compassion, life’s meaning, violence and predictions of future outcomes. However, what is not often addressed, but is increasingly desperately needed, is the realization of the evolutionary survival value of caring for others. This book strives to link our humanities and religious philosophies to a scientific understanding of human destiny, and provide a key to meaning in our lives. Though this idea has incubated for over two decades, recent extremism in Charlottesville and global threats of inhumanity and violence make this more timely than ever for all who care about who we are and our children’s future. Furthermore, our capacity for benefit or destruction of Homo sapiens or civilization as we know it sets a ticking timer on the urgency of this realization and focused action; we don’t have ‘forever’ to ‘get it!’
The recent introduction of optical coherence tomography angiography (OCTA) has remarkably expanded the knowledge of different retinal, chorioretinal, and optic disc disorders. OCTA is nowadays often used as a routine exam in clinical practice, which has significantly modified the approach to patients, granting the opportunity to easily and noninvasively investigate the retinal and choroidal circulation. Major experts in posterior eye imaging share in this publication their experiences, images and ideas using OCTA in various contexts including age-related macular degeneration, diabetic retinopathy and retinal dystrophies, thus providing an in-depth overview of the latest knowledge in this field.
There is a revolution in new glaucoma surgical techniques. New glaucoma surgical devices are taking precedence in glaucoma surgery, with the new surgeries drastically cutting down on the chances for patient infection as well as higher success rates compared to the older types of surgery. Surgical Innovations in Glaucoma is the only book of its kind written by the top experts in the field, from inventors, clinical trial investigators, and top specialists experienced with the new devices. Written for general ophthalmologists who perform glaucoma surgery, the text walks the reader through the what, where, when, and how of the new glaucoma surgical tools, and includes supplementary online how-to videos for those interested in seeing the latest glaucoma procedures performed with these devices.
Genetics and Genomics of Eye Disease: Advancing to Precision Medicine thoroughly examines the latest genomics methods for studying eye disease, including complex eye disorders associated with multiple genes. GWAS, WES, WGS, RNA-sequencing, and transcriptome analysis as employed in ocular genomics are discussed in-depth, as are genomics findings tied to early-onset glaucoma, strabismus, age-related macular degeneration, adult-onset glaucoma, diabetic retinopathy, keratoconus, and leber congenital amaurosis, among other diseases. Research and clinical specialists offer guidance on conducting preventative screenings and counseling patients, as well as the promise of machine learning, computational statistics and artificial intelligence in advancing ocular genomics research. - Offers thorough guidance on conducting genetic and genomic studies of eye disease - Examines the genetic basis of a wide range of complex eye diseases and single-gene and Mendelian disorders - Discusses the application of genetic testing and genetic risk prediction in eye disease diagnosis and patient counseling