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Mechanobiology
This book covers the proceedings of the Fifth Symposium on Mechanobiology of Cartilage and Chondrocyte. Mechanobiology can be now considered as a vigorous branch of biomechanics, biorheology and physiology mainly concerned with the study of the influence of mechanical forces on cells and tissues and their clinical or therapeutical applications. As we are now in the age of proteomics, genomics and cell micro mechanical approaches, suing methods like laser tweezers or confocal microscopy, mechanobiology brings new challenges. With such new research, mechanobiology promises new diagnostic and therapeutic approaches. In other respect there has been increasing interest over recent years in the fundamental role played by local mechanical parameters in chondrocyte regulations and cartilage dysfunctions as a first step in the development of osteoarthritis. These proceedings are sub-divided into four parts: Theoretical approaches and mechanobiology of chondrocyte; Cartilage and chondrocyte studies; Osteoarthritis: inflammation degradation and clinical approaches; and, Cartilage engineering
Multiscale Modeling of Developmental Systems
Mathematical and computational biology is playing an increasingly important role in the biological sciences. This science brings forward unique challenges, many of which are, at the moment, beyond the theoretical techniques available. Developmental biology, due to its complexity, has lagged somewhat behind its sister disciplines (such as molecular biology and population biology) in making use of quantitative modeling to further biological understanding. This volume comprises work that is among the best developmental modeling available and we feel it will do much to remedy this situation.This book is aimed at all those with an interest in the interdisciplinary field of computer and mathematic...
The Mitochondrion in the Germline and Early Development
Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. These volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology. - Includes many descriptive figures - Topics covered include the role of mitochondrial function, the use of ARTs to regulate mtDNA disease, nuclear transfer, and more - Latest volume in the series that covers 10 reviews from leading authorities in developmental biology
Evolution and Development
The marriage of evolutionary biology with developmental biology has resulted in the formation of a new field, evolutionary developmental biology, or "evo-devo. This volume reviews current research findings and thought in the broad field of evo-devo, looking at the developmental genetic mechanisms that cause variation and how alterations of these mechanisms can generate novel structural changes in a variety of plant and animal life. - Reviews current research findings and thought on evolutionary developmental biology, providing researchers an overview and synthesis of the latest research findings and contemporary thought in the area - Includes chapters discussing the evolutionary development of a wide variety of organisms and allows researchers to compare and contrast how genes are expressed in a variety of organisms—from fly to frog, to humans - Emphasizes the role of regulatory DNA in evolutionary development to give researchers perspective on how the regions of the genome that control gene expression and the protein factors that bind them are ultimately responsible for the diversity of life that has evolved
Principles of Tissue Engineering
Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world's experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material scie...
Basic Orthopaedic Biomechanics & Mechano-biology
Biomaterials / Ahmed El-Ghannam and Paul Ducheyne -- Biomechanics of the spine / Ian A. F. Stokes and James C. Iatridis -- Biomechanics of fracture fixation and fracture healing / Lutz E. Claes and Keita Ito -- Biomechanics and preclinical testing of artificial joints: the hip / Rik Huiskes and Jan Stolk -- Biomechanics of total knee replacement designs / Peter S. Walker.
Design and the Elastic Mind
In the past few decades, individuals have experienced dramatic changes in some of the most established dimensions of human life: time, space, matter, and individuality. Minds today must be able to synthesize such transformations, whether they are working across several time zones, travelling between satellite maps and nanoscale images, drowning in information, or acting fast in order to preserve some slow downtime. Design and the Elastic Mind focuses on designers ability to grasp momentous advances in technology, science and social mores and convert them into useful objects and systems. The projects included range from nanodevices to vehicles, appliances to interfaces and building facades, pragmatic solutions for everyday use to provocative ideas meant to influence our future choices. Designed by award-winning book designer Irma Boom, this volume also features essays by Paola Antonelli; design critic and historian Hugh Aldersey- Williams; visualization design expert Peter Hall; and nanophysicist Ted Sargent that further explore the promising relationship between design and science.
Transcriptional Switches During Development
This new volume in the Current Topics in Developmental Biology series concentrates on transcriptional switches during development. It includes chapters on such topics as muscle diversity, transcriptional response to genome structural variation, and the temporal gene network in Drosophila neural stem cells. With an international team of authors, this volume is a must-have addition for researchers and students alike. Concentrates on transcriptional switches during development Includes chapters on such topics as muscle diversity, transcriptional response to genome structural variation, and the temporal gene network in Drosophila neural stem cells With an international team of authors, this volume is a must-have addition for researchers and students alike
Current Topics in Developmental Biology
Together with other volumes in this series, Volume 58 presents thoughtful and forward-looking articles on developmental biology and developmental medicine. Reviews include:* A role for endogenous electric fields in wound healing* The role of mitotic checkpoint in maintaining genomic stability * The regulation of oocyte maturation* Stem cells: A promising source of pancreatic islets for transplantation in type 1 diabetes* Differentiation potential of adipose derived adult stem (ASAS) cellsThe exceptional reviews in this volume of Current Topics in Developmental Biology will be valuable to both clinical and fundamental researchers, as well as students and other professionals who want an introduction to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development.* Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine* The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
