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Where Does All That Food Go?
Most of us eat (or incorporate into our bodies) quite a bit of stuff that does not look, act or function even remotely like us. Unless our food mysteriously disappears inside of us, this must mean we change its molecular structure in some way. In fact, we are constantly modifying our molecules through chemical reactions, which together constitute our Metabolism. At any given moment, we transform (metabolize) millions of molecules within our bodies, building new ones, breaking down others, and exchanging them with the world around us. Metabolism is much more than the reason you gain weight when you overeat, it is a process that is so central for life that it defines what a living being is. We...
Essential Aspects of Immunometabolism in Health and Disease
Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different i...
Dietary Zn and Human Health
This book is a printed edition of the Special Issue "Dietary Zn and Human Health" that was published in Nutrients
Tools and Trends in Bioanalytical Chemistry
This textbook covers the main tools and techniques used in bioanalysis, provides an overview of their principles, and offers several examples of their application and future trends in diagnosis. Chapters from expert contributors explore the role of bioanalysis in different areas such as biochemistry, physiology, forensics, and clinical diagnosis, including topics from sampling/sample preparation, chemometrics in bioanalysis to the latest techniques used in the field. Particular attention is given to the recent advances in the application of mass spectrometry, NMR, electrochemical methods and separation techniques in bioanalysis. Readers will also find more about the application of microchip-based devices and analytical microarrays. This textbook will appeal to graduate/advanced undergraduate students in Chemistry, Biology, Biochemistry, Pharmacy, and Chemical Engineering. It is also a useful resource for researchers and professionals working in the fields of biomedicine and veterinary sciences, with clear explanations and examples of how the different bioanalytical devices are applied for clinical diagnosis.
Que bobagem!
"A maioria das pessoas parece ter, pelo menos, uma pseudociência de estimação. Ficaremos satisfeitos, nestes casos, em plantar no mínimo uma semente de ceticismo que leve o leitor a considerar: será?" "Energias curativas, bolinhas de açúcar mágicas, terapias que invocam os antepassados e maluquices inventadas sobre o poder avassalador dos desejos inconscientes operam, todas, sob 'leis de tapete voador'. Podem render boas metáforas, boa literatura, boa retórica, mas assim como a Odisseia não prova que os deuses do Olimpo existem, uma história bem contada não é necessariamente uma história real." "Buscamos oferecer uma vacina para o pensamento mágico, um manual para reconhecer ...
Formal Issues in Lexical-Functional Grammar
Lexical-Functional Grammar was first developed by Joan Bresnan and Ronald M. Kaplan in the late 1970s, and was designed to serve as a medium for expressing and explaining important generalisations about the syntax of human languages and thus to serve as a vehicle for independent linguistic research. An equally important goal was to provide a restricted, mathematically tractable notation that could be interpreted by psychologically plausible and computationally efficient processing mechanisms. The formal architecture of LFG provides a simple set of devices for describing the common properties of all human languages and the particular properties of individual languages. This volume presents work conducted over the past several years at the Xerox Palo Alto Research Center, Stanford University, and elsewhere. The different sections link mathematical and computational issues and the analysis of particular linguistic phenomena in areas such as wh-constructions, anaphoric binding, word order and coordination.
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New Advances on Zika Virus Research
Zika virus (ZIKV) is a mosquito-borne member of the Flaviviridae family that historically has been associated with mild febrile illness. However, the recent outbreaks in Brazil in 2015 and its rapid spread throughout South and Central America and the Caribbean, together with its association with severe neurological disorders—including fetal microcephaly and Guillain-Barré syndrome in adults—have changed the historic perspective of ZIKV. Currently, ZIKV is considered an important public health concern that has the potential to affect millions of people worldwide. The significance of ZIKV in human health and the lack of approved vaccines and/or antiviral drugs to combat ZIKV infection have triggered a global effort to develop effective countermeasures to prevent and/or treat ZIKV infection. In this Special Issue of Viruses, we have assembled a collection of 32 research and review articles that cover the more recent advances on ZIKV molecular biology, replication and transmission, virus–host interactions, pathogenesis, epidemiology, vaccine development, antivirals, and viral diagnosis.
Recent Advances in Manufacturing Modelling and Optimization
This book presents the selected proceedings of 2nd International Conference on Recent Advances in Manufacturing (RAM 2021). The book provides insights to current research trends and opportunities in modelling and optimization of manufacturing processes and systems. The topics covered include modelling analysis, computing and simulation, traditional and non-traditional optimization techniques, surface coating methods, additive manufacturing processes, CAD/CAM, robotics and automation, welding and joining processes, supply chain management and CAE and reverse engineering. This book will be a good reference for beginners, researchers and professionals interested in modelling and optimization related to manufacturing engineering and related fields.
