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Printed Edition of the Special Issue Published in IJMS
MicroRNA in Human Malignancies offers a deep overview of the role and translational significance of miRNAs in the development of cancer and other malignancies. The book establishes the foundations of the field by covering essential mechanisms and the translational potential of miRNAs in the field of oncology. Specific topics covered include invasion and metastasis, miRNAs and metabolism, and opportunities of miRNAs in therapeutics. Chapters on diseases include content on disease-related pathophysiology, as well as diagnostic, prognostic and predictive value. This book is an essential reference for students entering the field, as well as researchers and investigators. - Provides fundamental and translational chapters that facilitate the acquisition of knowledge needed to design and perform innovative miRNA-related research studies - Synthesizes current research, with a critical review on the field - Offers in-depth research by leading experts in the field
It features 200 works by 120 artists, including paintings by Futurism's main protagonists and there are also pieces by an array of modern and contemporary artists influenced by the Futurists.
MicroRNAs (miRNAs), which are a type of short non-coding RNA, are involved in number of processes, such as differentiation, development, inflammation, immune response, and cancer. miRNAs, which act as oncogenes or tumor suppressor genes, can control and regulate the translation and stability of target messenger RNA, contributing to cancer pathogenesis. Despite the progress that has been made in discovering the mechanisms of how miRNAs function in tumors, many questions and aspects of miRNA biology and processing still remain to be determined. This Special Issue, titled "MicroRNA in Solid Tumor and Hematological Diseases", provides a panorama of the existing knowledge gaps and potential uses of microRNAs to predict clinical outcome or response to therapies and provides evidence to explain their role as biomarkers to modulate the biological pathways that are critical for cancer development and progression. It includes eleven peer-reviewed papers that cover the role of microRNAs in different tumor types and their potential applications in diagnosis and clinical approaches.
This is the true-life story of a boy who quit school to become an apprentice on Savile Row, home to London's most venerable tailors, and wound up owning his own shop on the world-famous 'Golden Mile', where he hand-cuts exquisite suits for a clientele including royalty, politicians, literati, business tycoons, and media stars. On a bright, bitterly cold and snowy morning in January 1982, 17-year-old Richard Anderson made his way with his father to an interview at Savile Row's illustrious Henry Huntsman & Sons. They were late, but Richard got the job, with its meagre salary of only £2,000 a year, and his life was changed forever. Huntsman was arguably the world's most prestigious tailoring h...
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Mindenki életében van egy fordulópont. Egy olyan éles, tiszta pillanat, amikor az ember úgy érzi, mintha mellbe vágták volna, és teljes bizonyossággal, a kétség legkisebb árnyéka nélkül tudja, hogy élete már sohasem lesz olyan, mint addig volt. Michael Stirling életében ez a pillanat akkor jött el, amikor megpillantotta Franceska Bridgertont. Egész addigi életében nők után kajtatott vagy kajánul hagyta magát utolérni, ha a hölgyek üldözték, ölelte, csókolta őket, szeretkezett velük, de soha, egyetlen egyszer sem hagyta, hogy a szívét is dédelgessék. És ő, éppen ő, egyetlen pillantást vetett Francesca Bridgertonra és egy szempillantás alatt szer...