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Molecular Oncology
  • Language: en
  • Pages: 985

Molecular Oncology

Reviews the origins of molecular oncology, including technologies for cancer analysis, key pathways in human malignancies, and available pharmacologic therapies.

Lymphoma
  • Language: en
  • Pages: 325

Lymphoma

Major advances have occurred in the diagnosis and treatment of lymphoma in recent years. Our understanding of the molecular biology and genetics of the disease has increased exponentially, and significant imaging developments have resulted in earlier and more accurate diagnosis. The new edition of this landmark text places these advances in the context of daily clinical practice. Each chapter has been updated to reflect recent developments, including new treatment agents such as immunomodulatory drugs and the next generation of antibodies, and the increasing prognostic role of PET scanning. Results from recent large-scale clinical trials are presented, and pathology and cytogenetics are integrated into discussion of each disease entity, enabling the reader to review all the key diagnostic information in one place. Featuring many color illustrations, and written and edited by leading authorities in the field, Lymphoma provides all the information you need to diagnose and manage these complex disorders.

Lymphoma
  • Language: en
  • Pages: 414

Lymphoma

Recently, understanding the molecular pathogenesis of malignant lymphomas has led to improvement in the diagnostic precision and to the identification of a variety of molecular therapeutic targets. In addition, new drugs have been approved in the US and Europe, resulting in changes in the standard of care of several types of lymphoid malignancies. Comprehensive in scope and developed by a team of internationally renowned authors, Lymphoma: Diagnosis and Treatment provides a timely update on the most important advances in the biology, diagnosis, and therapy of lymphomas. As part of the Current Clinical Oncology series, Lymphoma: Diagnosis and Treatment will be of value to medical oncologists, hematologists, radiation oncologists, and all physicians involved in the care of patients with lymphoid malignancies.

The Grotesque Dancer on the Eighteenth-century Stage
  • Language: en
  • Pages: 404

The Grotesque Dancer on the Eighteenth-century Stage

Italian ballet in the eighteenth century was dominated by dancers trained in the style known as "grotesque"—a virtuoso style that combined French ballet technique with a vigorous athleticism that made Italian dancers in demand all over Europe. Gennaro Magri’s Trattato teorico-prattico di ballo, the only work from the eighteenth century that explains the practices of midcentury Italian theatrical dancing, is a starting point for investigating this influential type of ballet and its connections to the operatic and theatrical genres of its day. The Grotesque Dancer on the Eighteenth-Century Stage examines the theatrical world of the ballerino grottesco, Magri’s own career as a dancer in I...

Extranodal Lymphomas
  • Language: en
  • Pages: 344

Extranodal Lymphomas

  • Type: Book
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  • Published: 2008-07-25
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  • Publisher: CRC Press

Lymphomas classically manifest themselves in the lymph nodes but can also present in other bodily tissues or systems; the organ where exactly they present may make a very great difference to the strategy that should be adopted for their management. This topic has only recently been consistently addressed as an issue on its own, apart from the rest

Stochastic Methods in Cancer Research. Applications to Genomics and Angiogenesis
  • Language: en
  • Pages: 301

Stochastic Methods in Cancer Research. Applications to Genomics and Angiogenesis

  • Type: Book
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  • Published: 2011
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  • Publisher: Ledizioni

In this thesis, I study three stochastic methods that can be applied for the analysis of data in cancer research and, in particular, to cancer genomic data and to images of angiogenic processes. Cancer is a multistep process where the accumulation of genomic lesions alters cell biology. The latter is under control of several pathways and thus, cancer can arise via different mechanisms affecting different pathways. Due to the general complexity of this disease and the different types of tumors, the efforts of cancer research cover several research areas such as, for example, immunology, genetics, cell biology, angiogenesis.

The Cheating Cell
  • Language: en
  • Pages: 256

The Cheating Cell

A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked because the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of cont...

Cancer Genomics
  • Language: en
  • Pages: 591

Cancer Genomics

The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with its propensity to metastasize and to respond to therapy. It is not just one or a few genes, it is the complex alteration of the genome that determines cancer development and progression. Future management of cancer patients will therefore rely on thorough molecular analyses of each single case. Through this book, students, researchers and oncologists will obtain a comprehensive picture of what the first ten years of cancer genomics have revealed. Experts in the field describe, cancer by cancer, the progress made and its implications for diagnosis, prognosis and treatment of cancer. The deep impact on the clinics and the challenge for future translational research become evident.

Marine Biotechnology, Revealing an Ocean of Opportunities
  • Language: en
  • Pages: 420