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Cranial, Craniofacial and Skull Base Surgery
The Fruits of Reinvention Surgery related to the human head, its compartment and contents has been reinvented over the past 40 years. A number of instruments, most notably the sophisticated medical imaging device and the operating microscope, have principally fueled this evolution. Along the way, endoscopy and sophisticated navigation capabilities have added to the realization of a unique comprehension of normal and abnormal microanatomy permitting corridors and manipu- tions that allow novel strategies for surgery in these highly vital functional areas. Cappabianca, Califano and Iaconetta have created a detailed and fully modern review of methods and strategies related to complex surgery an...
The Power of Urban Water
Water is a global resource for modern societies - and water was a global resource for pre-modern societies. The many different water systems serving processes of urbanisation and urban life in ancient times and the Middle Ages have hardly been researched until now. The numerous contributions to this volume pose questions such as what the basic cultural significance of water was, the power of water, in the town and for the town, from different points of view. Symbolic, aesthetic, and cult aspects are taken up, as is the role of water in politics, society, and economy, in daily life, but also in processes of urban planning or in urban neighbourhoods. Not least, the dangers of polluted water or of flooding presented a challenge to urban society. The contributions in this volume draw attention to the complex, manifold relations between water and human beings. This collection presents the results of an international conference in Kiel in 2018. It is directed towards both scholars in ancient and mediaeval studies and all those interested in the diversity of water systems in urban space in ancient and mediaeval times.
Stroke-Vascular Diseases
Atherosclerosis, the underlying cause of heart attacks, strokes and peripheral vascular disease, is one of the major killers in the world. By 2020 WHO statistics indicate that it will be the most common cause of morbidity and mortality in both the industrialised world and the underdeveloped world. The disease develops slowly over many years in the innermost layer of large and medium-sized arteries (Fig. 1) (Scott, 1995; Ross, 1999; Naumova and Scott, 2000; Glass and Witztum, 2001; Libby, 2001). It does not usually become manifest before the fourth of fifth decade, but then often strikes with devas tating suddenness. Fifty per cent of individuals still die (25 per cent immedi ately) from thei...
Brain Tumors
Brain Tumors: Current and Emerging Therapeutic Strategies focuses on tumor models, the molecular mechanisms involved in the pathogenesis of this disease, and on the new diagnostic and treatment strategies utilized to stage and treat this malignancy. A special section on immunotherapy and gene therapy provides the most up-to-date information on the pre-clinical and clinical advances of this therapeutic venue. Each chapter in Brain Tumors: Current and Emerging Therapeutic Strategies is authored by international experts with extensive experience in the areas covered.
From Nucleic Acids Sequences to Molecular Medicine
Despite a half century of structural, biophysical and biochemical investigations of ribonucleic acids, they are still mysterious. RNAs stand at fertile crossroads of disciplines, integrating concepts from genomics, proteomics, dynamics as well as biochemistry and molecular biology. From 20 years it is clear, that genetic regulation of eukaryotic organisms has been misunderstood for the last years that the expression of genetic information is effected only by proteins. Basic understanding of nucleic acids has enhanced our foundation to probe novel biological functions. This is especially evident for RNA molecules whose functionality, maturation, and regulation require formation of correct secondary structure through encoded base-pairing interactions.
Bioengineered Nanomaterials
Many varieties of new, complex diseases are constantly being discovered, which leaves scientists with little choice but to embrace innovative methods for controlling the invasion of life-threatening problems. The use of nanotechnology has given scientists an opportunity to create nanomaterials that could help medical professionals in diagnosing and treating problems quickly and effectively. Bioengineered Nanomaterials presents in-depth information on bioengineered nanomaterials currently being developed in leading research laboratories around the world. In particular, the book focuses on nanomaterials for biomedical applications. This collection brings together novel methodologies and strate...
Ancient Crete: Oxford Bibliographies Online Research Guide
This ebook is a selective guide designed to help scholars and students of the ancient world find reliable sources of information by directing them to the best available scholarly materials in whatever form or format they appear from books, chapters, and journal articles to online archives, electronic data sets, and blogs. Written by a leading international authority on the subject, the ebook provides bibliographic information supported by direct recommendations about which sources to consult and editorial commentary to make it clear how the cited sources are interrelated. A reader will discover, for instance, the most reliable introductions and overviews to the topic, and the most important ...
Midline Skull Base Surgery
This richly illustrated book offers detailed, step-by-step guidance on surgical approaches and techniques in patients with midline tumors of the skull base. Access routes are described from both endoscopic and microscopic standpoints, via different approaches, in order to provide a 360-degree overview of contemporary midline skull base surgery. For each pathology, the multiple surgical options and their specific indications are clearly presented, with inclusion of neuroradiological images, an anatomical dissection study and operative images and videos. The book is intended for surgeons who wish to acquire knowledge and experience in skull base surgery employing endoscopic endonasal and microsurgical transcranial techniques. It is exceptional in providing an integrated perspective that encompasses traditional microsurgical approaches and the most recent endoscopic ones, with definition of the indications for and limitations of both options.
Il tesoro di Minos
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