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Molecular genetics has revolutionized our understanding of the susceptibility to and pathogenesis of cancer and is heralding the era of ‘molecular oncology’. This progress is well illustrated by the gain in knowledge accumulated since the release of ‘Familial Cancer’ in 1985 - known among experts as the ‘yellow book’. Cancer genes can now be identified, mapped and sequenced, and this technology has resulted in presymptomatic testing of persons at risk and the development of preventive therapeutic measures. This book provides an update of the latest advances by international experts in the field of hereditary cancer, with special emphasis on the needs of medical practice. The firs...
A New Strategy Toward Cancer Control. Still in its infancy, the familial/hereditary approach to cancer control is proving to be one of the most potent strategies in the war on cancer. Over the past few years the human genome project has generated an abundance of valuable information on the genetic origins of a range of cancers. Tests now exist for several hereditary, tumor-promoting genetic mutations-including those found in BRCA genes associated with breast cancer as well as mutations of HNPCC genes which have been linked to colon cancers-and many more are anticipated in the near future. Armed with the information yielded by these tests, physicians have already saved countless lives through...
In this book, Marc Rodwin examines the development of conflicts of interest in the health care systems of the US, France, and Japan. He shows that national differences in the organization of medical practice and the interplay of organized medicine, the market, and the state give rise to variations in the type and prevalence of such conflicts, and then analyzes the strategies that each nation employs to cope with them. Drawing on the experiences of these three nations, Conflicts of Interest and the Future of Medicine demonstrates that we can mitigate these problems with carefully planned reform and regulation.
Winner, 2011 Best Book in the History of Medicine, European Association for the History of Medicine and Health Modern scientific tools can identify a genetic predisposition to cancer before any disease is detectable. Some women will never develop breast or ovarian cancer, but they nevertheless must decide, as a result of genetic testing, whether to have their breasts and ovaries removed to avoid the possibility of disease. The striking contrast between the sophistication of diagnosis and the crudeness of preventive surgery forms the basis of historian Ilana Löwy’s important study. Löwy traces the history of prophylactic amputations through a century of preventive treatment and back to a ...
A narrative-driven exploration of the effects of BRCA genetic testing on the lives of at-risk women
Chronicles the various campaigns waged against breast cancer and its effects on women during the last century.
The book illustrates how this applies to the future of application system development, especially how it informs and affects Web services and business rule-based approaches, and how semantics will play out with XML and the semantic Web. The book also contains a quick reference guide to related terms and technologies.
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This book brings together examples and cases from across the world to discuss how sport has and can further contribute to the UN 2030 Sustainable Development agenda. It discusses the major steps that international bodies have taken so far and can further take in the progressive integration of sport for sustainable development. Contributors from 21 countries take up at least one of the 17 UNO Sport for Development and Peace goals, and present and analyse examples of national, regional or local policies using sport as a lever for sustainable development. From traditional games to major competitions, from gender equality to social development and developing governmental transparency, the chapte...