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Parkinson's Disease
Parkinson's disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and many decades of research, the origin of the pathogenesis and the molecular determinants involved in the disorder has remained elusive. Confounding this issue is the lack of experimental models that completely recapitulate the disease state. The identification of a number of genes thought to play a role in the cell death, and development of both toxin and genetic models to explore the function of the genes both in unaffected and diseased cells are now providing new insights into the molecular basis of the neuro...
Fraser's Magazine for Town and Country
Contains the first printing of Sartor resartus, as well as other works by Thomas Carlyle.
Australia goes to Washington
Since 1940, when an Australian legation was established in Washington DC, Australian governments have expected much from their representatives in the American capital. This book brings together expert analyses of those who have served as heads of mission and of the challenges they have faced. Ranging beyond conventional studies of the Australian–United States relationship, it provides insights into the dynamics between Australian and US policymakers and into the culture of one of Australia’s oldest and most important overseas missions. It provides an appreciation of the importance of the embassy and the head of mission in Washington in mediating the relationship between Australia and the United States and of their role in managing expectations in Canberra and Washington. Australia Goes to Washington also sheds new light on personal trials and achievements at the coalface of Australian–United States relations.
Secret Edinburgh
Explore Edinburgh’s secret history through a fascinating selection of stories, facts and photographs.
Haddington Through Time
This fascinating selection of photographs traces some of the many ways in which Haddington has changed and developed over the last century.
Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disease in the world. Still the only major text on the subject, the completely revised and updated second edition of Parkinson's Disease: Diagnosis and Clinical Management comes at a time when specialists have made important advances in our understanding of the etiology, pathogenesis, investigation, and management of Parkinson's disease. The book includes 23 completely new chapters, and has updated information on: Genetics Pathology Biomarkers Pathogenesis Impulse control disorders in Parkinson's disease Updated outcome measures Complementary and alternative medicine for the treatment of Parkinson's disease Together the chapters form a comprehensive review of the many issues facing PD physicians today. Lucid and easily readable from beginning to end, each chapter may also stand on its own as a scholarly review of the individual subject. Each one is concisely written and heavily referenced for this purpose. The second edition of Parkinson's Disease: Diagnosis and Clinical Management provides a state-of-the-art review of where we've been, where we are now, and where we are going in treating this disease.
