You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
None
G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses. They dimerize (form a pair of macromolecules) with a wide variety of other receptors. The proposed book will provide a comprehensive overview of GPCR dimers, starting with a historical perspective and including, basic information about the different dimers, how they synthesize, their signaling properties, and the many diverse physiological processes in which they are involved. In addition to presenting information about healthy GPCR dimer activity, the book will also include a section on their pathology and therapeutic potentials.
Finally! There is a definitive reference guide available for harmonicas in each and every key. This ground breaking series unlocks the musical power of the 10-hole major diatonic harmonica. One key at a time, each is designed to present detailed musical information for beginners, intermediate and advanced players who are either music readers or non-reading players. Learn the notes, intervals, bends, overbends, dyads, chords, arpeggios, modes and scales that are specific to each harmonica key. There is also a special section in each book showing other types of diatonic harmonicas and the variations unique to them like—extreme bending, low-tuned, octave and tremolo-tuned models and more.Have...
The past decade has seen tremendous advances in the study of G protein-coupled receptors (GPCRs), including the molecular cloning and identification of more than 100 hundred GPCR genes. But while GPCRs serve as targets for more than 300 medicines in the modern pharmacopoeia, the shrinking pool of known ligands and the continuing discovery of orphan GPCR genes have underscored the need for new approaches to ligand identification. Identification and Expression of G Protein-Coupled Receptors addresses this new direction in GPCR biochemistry-offering a definitive laboratory bench manual that emphasizes expression over primary cloning strategies. In a series of expert contributions by well-known ...
Slack enjoyed full access to Hutchinson's archives and conducted extensive interviews both with Hutchinson himself and with his students, colleagues, and friends. She evaluates his contributions to theoretical ecology, limnology (the study of fresh-water ecosystems), biogeochemistry, population ecology, and the creation of the new fields of systems ecology and radiation ecology, and she discusses his profound influence as a mentor. The book also looks into his personal life, which included three very different wives, a refugee baby under his care during World War II, friendships with such contemporaries as Rebecca West, Margaret Mead, and Gregory Bateson, and a host of colleagues and friends on four continents. Filled with information available nowhere else, this book draws a vibrant portrait of a giant in the discipline of twentieth-century ecology who was also a man of remarkable personal appeal. --Book Jacket.
Alan V. Smrcka presents a collection of cutting-edge methods for investigating G protein signaling from a variety of perspectives ranging from in vitro biochemistry to whole animal studies. Among the readily reproducible techniques presented are those for the purification of G proteins and effectors enzymes, assays of these purified G proteins and effector enzymes, and for the study of G proteins interactions with effectors in intact cells. Additional methods are provided for assaying G protein coupled receptor structure, function, and localization, and for studying the physiological roles for endogenous G proteins.
Covering recently developed methods in membrane-bound receptors, this book emphasizes receptor structure and function, knowledge of which is essential to the study of signal transduction. G Protein-Coupled Receptors has culled contributors from domestic and international sources, providing a broad base of knowledge. Some topics covered are the r