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The Interferons
At long last, the first book to cover all important areas of interferon science in one volume. Top scientists, including many pioneers in the field, highlight the role of interferons as research tools and as therapeutic agents in clinical applications. Edited by an experienced interferonologist, chapters include discussions of interferon genes, Type I, II and III IFNs, as well as their induction, production and purification, receptors actions, measuring IFN activities and anti-IFN antibodies, as well as the evolution of viral defense mechanisms. For immunologists, cancer researchers, medicinal chemists, cell biologists, developmental biologists and the pharmaceutical industry.
Dynamic Capabilities Between Firm Organisation and Local Systems of Production
This book offers an analysis of how firms manage to reconfigure their pool of resources, to deal with the turbulent environments in which they are embedded, thus tackling the issue of how dynamic capabilities must be defined and conceptualized.
Isoperimetric Inequalities in Riemannian Manifolds
This work gives a coherent introduction to isoperimetric inequalities in Riemannian manifolds, featuring many of the results obtained during the last 25 years and discussing different techniques in the area. Written in a clear and appealing style, the book includes sufficient introductory material, making it also accessible to graduate students. It will be of interest to researchers working on geometric inequalities either from a geometric or analytic point of view, but also to those interested in applying the described techniques to their field.
Modelling and Simulation for Autonomous Systems
This book constitutes the thoroughly refereed post-workshop proceedings of the First International Workshop on Modelling and Simulation for Autonomous Systems, MESAS 2014, held in Rome, Italy, in May 2014. The 32 revised full papers included in the volume were carefully reviewed and selected from 50 submissions, of which 46 were presented at the workshop. They are organized in the following topical sections: unmanned aerial vehicle, distributed simulation, robot system, military application, validation, human-machine communication, gazebo simulator, and algorithm.
Collaboration in a Data-Rich World
This book constitutes the refereed proceedings of the 18th IFIP WG 5.5 Working Conference on Virtual Enterprises, PRO-VE 2017, held in Vicenza, Italy, in September 2017. The 68 revised full papers were carefully reviewed and selected from 159 submissions. They provide a comprehensive overview of identified challenges and recent advances in various collaborative network (CN) domains and their applications, with a strong focus on the following areas: collaborative models, platforms and systems for data-rich worlds; manufacturing ecosystem and collaboration in Industry 4.0; big data analytics and intelligence; risk, performance, and uncertainty in collaborative data-rich systems; semantic data/service discovery, retrieval, and composition in a collaborative data-rich world; trust and sustainability analysis in collaborative networks; value creation and social impact of collaboration in data-rich worlds; technology development platforms supporting collaborative systems; collective intelligence and collaboration in advanced/emerging applications: collaborative manufacturing and factories of the future, e-health and care, food and agribusiness, and crisis/disaster management.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Effects of Iodine Intake on Human Health
Iodine, a key component of thyroid hormones, is considered an essential micronutrient for proper health at all life stages. Indeed, an inadequate dietary intake of iodine is responsible for several functional and developmental abnormalities. The most serious consequences of iodine deficiency include hypothyroidism, early abortion, low birth weight, preterm delivery, neurocognitive impairment, and mental retardation. On the other hand, the consequences of mild-to-moderate iodine deficiency, such as goiter, are less well understood but represent an important priority for research and public health practice. Over the last several decades, many countries across the globe have introduced mandatory salt iodization programs, which have dramatically reduced the number of iodine-deficient countries. However, despite substantial progress worldwide, mild-to-moderate deficiency is still prevalent even in many developed countries. Thus, the ongoing monitoring of the population iodine status remains crucially important, and attention may need to be paid to vulnerable life stage groups.
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