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Chromatin and Chromosomal Protein Research III
First multi-year cumulation covers six years: 1965-70.
Chromatin and Chromosomal Protein Research II
The underlying idea that cancer is a genetic disease at the cellular level was postulated over 75 years ago when Boveri hypothesised that the malignant cell was one that had obtained an abnormal chromatin content. However, it has been only the last decade where enormous strides have been made toward understanding neoplastic development. Explosive growth in the discipline of cancer genetics is so rapid that any attempt to review this subject becomes rapidly outdated and continuous revisions are warranted. Conclusive evidence has been reached associating specific chromosomal abnormalities to various cancers. We have just begun to characterise the genes, which are involved in these consistent c...
Vols. for 1970- incorporate research supported during the year following the report year.
Bioanalytical Chemistry provides a thorough introduction for students and practitioners with a broad range of backgrounds from chemistry to medicine. In so doing, it brings together many of the techniques commonly used by biochemists and molecular biologists. The text includes entire chapters on design and implementation of enzyme assays; mass spectrometry; and validation of new methods. Each chapter progresses from basic concepts to applications involving real samples, and ends with a set of problems, while an appendix contains selected answers. The authors have limited mathematical derivations to those that are essential for an understanding of each method and they include a list of suggested reading for further information. This textbook provides an ideal companion for students, researchers, and industrial scientists working in chemistry, biology, biochemistry, pharmacy, and medicine.
Biographic Memoirs: Volume 58 contains short biographies of deceased members of the National Academy of Sciences.
Within recent years, affinity chromatography has become established as one of the most potent separatory techniques available to the biochemist. The technique has been exploited in almost every area of biochemistry and its applications are rapidly infiltrating cellular biology, immunology, medicine and technology. Because of this explosive development, this book is not intended as a comprehensive account of all the available systems but rather as a guide to current trends. However, whilst the detailed methodology of these systems vary, they are based on common principles.The aim of this book is to delineate these common principles and show how they are applied in practice.