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There are only very few chemical classes of antibiotics in medical use, and these have originated over a span of more than 60 years of research. Almost half a century ago, the first member of the macrolides, erythromycin, was introduced as a treatment option for bacterial infections. Erythromycin is a very complex fermentation product obtained from the soil bacterium Saccharopolyspora ery thraea (originally named Streptomyces erythreus). The success of erythromycin, based on its efficacy and tolerability, stimulated researchers throughout the world to undertake intense efforts to understand the biology and chemistry of macrolides and to use this experience to improve the properties of this c...
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Since the publication of the last edition of Principles and Practice of Clinical Bacteriology, our understanding of bacterial genetics and pathogenicity has been transformed due to the availability of whole genome sequences and new technologies such as proteomics and transcriptomics. The present, completely revised second edition of this greatly valued work has been developed to integrate this new knowledge in a clinically relevant manner. Principles and Practice of Clinical Bacteriology, Second Edition, provides the reader with invaluable information on the parasitology, pathogenesis, epidemiology and treatment strategies for each pathogen while offering a succinct outline of the best current methods for diagnosis of human bacterial diseases. With contributions from an international team of experts in the field, this book is an invaluable reference work for all clinical microbiologists, infectious disease physicians, public health physicians and trainees within these disciplines.
First multi-year cumulation covers six years: 1965-70.
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A general resource for all subdisciplines of clinical microbiology to use when evaluating commercial methods, tests, or procedures. • Reviews all the commercially available tests (both manual and automated) in the discipline of clinical microbiology. • Includes a description of the sensitivities, specificities, and predictive values from peer-reviewed sources. • Features separate chapters devoted to molecular microbiology, information management, emerging infectious diseases, and veterinary clinical microbiology.