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Proceedings of an international symposium, held in Ulm, Germany, September 21-24, 1994
This monograph provides a comprehensive basis for understanding the complex interactions that take place between synaptic input, cellular properties, and the oscillatory output of a neural network, especially in the maturing or developing nervous system. Emphasis is placed on drawing a parallel betw
This book explores the role calcium signaling plays in cellular responses in almost all types of cells including airway smooth muscle cells. This universal signaling may result from extracellular calcium influx and/or intracellular calcium release, which are precisely controlled and regulated by ion channels, exchangers and/or transporters on the plasmalemmal or sarcoplasmic reticulum membrane. First, several chapters detail calcium release channels (ryanodine receptors and inositol trisphosphate receptors), voltage-dependent potassium channels, transient receptor potential channels, Orai channels, calcium-activated potassium channels, and calcium-activated chloride channels. Well-characteri...
The year 1924 was a game changer! For the first time, the profession as a whole had a way of gauging the nervous system via the NCM (neurocalometer.) This scientific leap revealed if aberrant spinal temperatures were present and, more importantly, when they were not.Today, we now understand that a temperature asymmetry as detected by thermography reflects function of the sympathetic nervous system. When the chiropractor implements thermography, not only are they able to obtain important neurological data but also equips the entire chiropractic profession with an objective analysis of when to adjust and when not to adjust. The philosophical and artistic constructs can be debated based on one's personal understanding. However, science (when applied objectively) cannot be argued.With what we currently know and understand about the nervous system, when a spinal compromise is present, the nervous system will always be affected. Thermography and its application thereof provide the chiropractor an objective neurological gauge. Moreover, it provides a unique way to not only keep the profession separate and distinct but to also unite the profession as a whole.
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This book provides a comprehensive, authoritative, and contemporary discussion of the physiology and pathophysiology of the chest wall as well as an overview of the diagnostic and therapeutic modalities. It is an invaluable aid to clinical investigators.
Mitochondria, often referred to as the “powerhouses” of the cell, generate adenosine triphosphate (ATP) by oxidative phosphorylation or OXPHOS, and maintain cellular homeostasis. In addition to generating ATP, mitochondria are involved in regulation of cell cycle, proliferation, free radical production, innate immune responses and apoptosis. Mitochondrial Function in Lung Health and Disease fills the current gap in the literature and outlines the growing clinical relevance of mitochondrial dysfunction. Currently, there is no overview on the role of mitochondria in pulmonary diseases and this volume focuses on the mitochondrial metabolism, redox signaling, and mechanisms of mitochondrial pathways in lung injury, inflammation, repair and remodeling. Furthermore, in addition to their well-recognized role in cellular energy production and apoptosis, mitochondria appear to play a role in many respiratory diseases and lung cancer. Chapters are written by top notch researchers and clinicians and outline the evidence for mitochondrial biogenesis in inhalational lung injury, COPD and asthma.
This second edition of the landmark 1991 text, Basic Mechanisms of Pediatric Respiratory Disease reviews the importance of the integrations of molecular, cellular and physiologic strategies in the development of a new understanding of pediatric respiratory disorders. It provides state-of-the-art information about fundamental mechanisms underlying ......
Offering the comprehensive, authoritative information needed for effective diagnosis, treatment, and management of sick and premature infants, Fetal and Neonatal Physiology, 6th Edition, is an invaluable resource for board review, clinical rounds, scientific research, and day-to-day practice. This trusted two-volume text synthesizes recent advances in the field into definitive guidance for today's busy practitioner, focusing on the basic science needed for exam preparation and key information required for full-time practice. It stands alone as the most complete text available in this complex and fast-changing field, yet is easy to use for everyday application. - Offers definitive guidance on...