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Experimentalists tend to revel in the complexity and multidimensionality of biological processes. Modelers, on the other hand, generally look towards parsimony as a guiding prin ciple in their approach to understanding physiological systems. It is therefore not surprising that a substantial degree of miscommunication and misunderstanding still exists between the two groups of truth-seekers. However, there have been numerous instances in physiology where the marriage of mathematical modeling and experimentation has led to powerful in sights into the mechanisms being studied. Respiratory control represents one area in which this kind of cross-pollination has proven particularly fruitful. While...
The fifth Oxford Conference was held on September 17th-19th, 1991, at the Fuji Institute of Training in Japan -the first time that the meeting has taken place in the Asian area. The facts that only a relatively few Japanese had attended previous Oxford Conferences and that Japan is far from other regions with possible participants made the organizers anticipate a small attendance at the meeting. However, contrary to our expectations, 198 active members (72 foreign and 126 domestic participants) submitted 146 papers from 15 countries. This was far beyond our preliminary estimate and could have caused problems in providing accommodation for the participants and in programming their scientific ...
**Selected for Doody's Core Titles® 2024 in Psychiatry**Anatomy of Neuropsychiatry: The New Anatomy of the Basal Forebrain and Its Implications for Neuropsychiatric Illness, Second Edition, builds upon reprised classic chapters by Lennart Heimer and Gary Van Hoesen describing the cortical and subcortical structure and functional involvements of several functional–anatomical macrosystems in the human forebrain, the existence of which obviates the vaunted heuristic value of the "limbic system" concept in the study of motivation and emotion. New narrative brings in important historical, philosophical, and histotechnical contexts, integration with novel technologies (e.g., optogenetics) and s...
This book is a record of the contents of the papers accepted by the Congress Committee for presentation at the Fourth International Congress of Cybernetics and Systems (Amsterdam, The Netherlands, 21-25 August 1978). Two hundred and forty-five papers from authors from thirty-three countries of all the five continents are included. The papers are presented in an abridged form in order to highlight the main themes and produce a book that is both readable and relatively inexpensive. It was felt that after the publication of the weighty and rather costly form of the Proceedings of the Third International Congress of Cybernetics and Systems held in Bucharest, Romania in 1975 (Modern Trends in Cyb...
Understanding the dynamic evolution of the yield curve is critical to many financial tasks, including pricing financial assets and their derivatives, managing financial risk, allocating portfolios, structuring fiscal debt, conducting monetary policy, and valuing capital goods. Unfortunately, most yield curve models tend to be theoretically rigorous but empirically disappointing, or empirically successful but theoretically lacking. In this book, Francis Diebold and Glenn Rudebusch propose two extensions of the classic yield curve model of Nelson and Siegel that are both theoretically rigorous and empirically successful. The first extension is the dynamic Nelson-Siegel model (DNS), while the s...
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Although it is well-accepted that drug addiction is a major public health concern, how we address it as a society continues to evolve as recent advances in the lab and clinic clarify the nature of the problem and influence our views. This unique collection of eight chapters reviews key findings on the neurobiology and therapeutics of addiction while capturing the diversity of perspectives that shape these concepts, which range from evolutionary biology to psychiatry to the legal system. This book discusses in depth how technological advances have led to important discoveries and how these discoveries, in turn, are increasingly being translated into clinical practice. It also presents avenues for future study that hold promise for the many affected by addiction.