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Evolution by Gene Duplication
It is said that "necessity is the mother of invention". To be sure, wheels and pulleys were invented out of necessity by the tenacious minds of upright citi zens. Looking at the history of mankind, however, one has to add that "Ieisure is the mother of cultural improvement". Man's creative genius flourished only when his mind, freed from the worry of daily toils, was permitted to entertain apparently useless thoughts. In the same manner, one might say with regard to evolution that "natural selection mere(y tnodifted, while redundanry created". Natural selection has been extremely effective in policing alleHe mutations which arise in already existing gene loci. Because of natural selection, o...
The Selfish Gene
With a new epilogue to the 40th anniversary edition.
The Selfish Gene
Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science
Gene Sharing and Evolution
In Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution.
The Gene
** NEW YORK TIMES NUMBER ONE BESTSELLER ** The Gene is the story of one of the most powerful and dangerous ideas in our history from the author of The Emperor of All Maladies. The story begins in an Augustinian abbey in 1856, and takes the reader from Darwin’s groundbreaking theory of evolution, to the horrors of Nazi eugenics, to present day and beyond - as we learn to “read” and “write” the human genome that unleashes the potential to change the fates and identities of our children. Majestic in its scope and ambition, The Gene provides us with a definitive account of the epic history of the quest to decipher the master-code that makes and defines humans – and paints a fascinati...
Exploring the Biological Contributions to Human Health
It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organ...
Identically Different
Since the discovery of DNA scientists have believed that genes are fixed entities that cannot be changed by environment - we inherit them, pass them on to our children and take them with us when we die. We can make choices that influence our environment, but we cannot change our genes. Or so we have long been prepared to believe. Professor Tim Spector reveals how the latest genetic research and his own pioneering studies are rewriting everything we thought we knew about genes, identity and evolution. Conceptually, he explains, our genes are not fixed entities but more like plastic, able to change shape and evolve, and these changes can be passed on to our children and grandchildren. In the face of these astonishing new discoveries, the old nature-nurture debate instantly dissolves and can be replaced with a much deeper understanding of our genes and the complex role they play in shaping our identities. Tim Spector's dazzling guide to the hidden world of our genes will make you think again about everything from sexuality to religion, cancer to autism, politics to pubic hair, clones to bacteria, and what it is that makes us all so unique and quintessentially human.
Fine Mapping of Ol-1, a Resistance Gene to Tomato Powdery Mildew (Oidium Neolycopersici)
In this study, after recombinant screening and disease test of BC1S2 population, Ol-1 gene was mapped between markers P13M49 and H9A11 with genetic distance of 0.26 cM on the long arm of chromosome 6 of tomato. The study also found out that marker H9A11 was located on one of the newly identified BAC (161G17) which in turn overlapping to 123G17 making the previous gap between the BACs no more relevant for fine mapping of Ol-1. BAC 215M16 have full sequence available while 123G17 has also been sequenced except a small gap (100bp). BAC 161G17 is also partially sequenced. Therefore, as future line of work, more markers will be generated based on the available sequence information of BACs and we will narrow down the Ol-1 region to a single gene very soon after another recombinant screening.
