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Allylic boron compounds have gained a prominent position as a truly practical class of synthetic reagents in the past twenty-five years. Their main application as a method for the stereoselective synthesis of homoallylic alcohols by allyl-transfer to carbonyl compounds is essentially unmatched. In this process, a new carbon-carbon bond is formed, and up to two new stereogenic centers are created in a predictably controlled manner. Highly effective and general enantioselective variants are available, with countless applications in the total syntheses of polyacetate and polypropionate natural products. Furthermore, the residual allylic unit can be manipulated through a number of different tran...
Organic Reactions is a collection of chapters, each devoted to a single reaction or a definitive phase of a reaction of wide applicability, with particular attention given to limitations, interfering influences, effects of structure, and the selection of experimental techniques. Volume 70 includes two chapters, the first takes a look at the Catalytic Asymmetric Strecker Reaction, the second at the Synthesis of Phenols and Quinones via Fischer Carbene Complexes. Includes tables that contain all possible examples of the reactions under consideration Each reaction is fully referenced to the primary literature
The 94th volume in this series for organic chemists in industry presents critical discussions of widely used organic reactions or particular phases of a reaction. The material is treated from a preparative viewpoint, with emphasis on limitations, interfering influences, effects of structure and the selection of experimental techniques. The work includes tables that contain all possible examples of the reaction under consideration. Detailed procedures illustrate the significant modifications of each method.