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Cancer Drug Resistance Research Perspectives
One of the main causes of failure in the treatment of cancer is the development of drug resistance by the cancer cells. The design of cancer chemotherapy has become increasingly sophisticated, yet there is no cancer treatment that is 100% effective against disseminated cancer. Resistance to treatment with anticancer drugs results from a variety of factors including individual variations in patients and somatic cell genetic differences in tumours, even those from the same tissue of origin. Frequently resistance is intrinsic to the cancer, but as therapy becomes more and more effective, acquired resistance has also become common. The most common reason for acquisition of resistance to a broad ...
Oncogene Proteins
Oncogene proteins are proteins coded by oncogenes. They include proteins resulting from the fusion of an oncogene and another gene (oncogene proteins, fusion). An oncogene is a modified gene, or a set of nucleotides that codes for a protein and is believed to cause cancer. This book brings together the latest research in this field from around the world.
Advances in Cancer Drug Targets
Advances in Cancer Drug Targets is an e-book series that brings together recent expert reviews published on the subject with a focus on strategies for synthesizing and isolating organic compounds and elucidating the structure and nature of DNA. The reviews presented in this series are written by experts in pharmaceutical sciences and molecular biology. These reviews have been carefully selected to present development of new approaches to anti-cancer therapy and anti-cancer drug development. The contents of this book include chapters on heat shock protein 90, spindle assembly checkpoint, ErbB receptors, anti-tumor effects of bisphosphonates, biomarkers for risk assessment and prevention of breast cancer, fibrates action in Daunorubicin chemical reaction and many more. The reference work serves to give readers a brief yet comprehensive glance at current theory and practice behind employing chemical compounds for tackling tumor suppression, DNA site specific drug targeting and the inhibition of enzymes involved in growth control pathways. This e-book volume will be of special interest to molecular biologists and pharmaceutical scientists.
Southeast Asian Personalities of Chinese Descent
"This is a bold project recording the lives of a particular group of Southeast Asians. Most of the people whose biographies are included here have settled down in the ten countries that constitute the region. Each of them has either self-identified as Chinese or is comfortable to be known as someone of Chinese ancestry. There are also those who were born in China or elsewhere who came here to work and do business, including seeking help from others who have ethnic Chinese connections. With the political and economic conditions of the region in a great state of flux for the past two centuries, it is impossible to find consistency in the naming process. Confucius had stressed that correct name...
Southeast Asian Personalities of Chinese Descent: Glossary and index
This is a bold project recording the lives of a particular group of Southeast Asians. Most of the people whose biographies are included here have settled down in the ten countries that constitute the region. Each of them has either self-identified as Chinese or is comfortable to be known as someone of Chinese ancestry. There are also those who were born in China or elsewhere who came here to work and do business, including seeking help from others who have ethnic Chinese connections. With the political and economic conditions of the region in a great state of flux for the past two centuries, it is impossible to find consistency in the naming process. Confucius had stressed that correct names...
Biomaterials
Explores Biomedical Science from a Unique Perspective Biomaterials: A Basic Introduction is a definitive resource for students entering biomedical or bioengineering disciplines. This text offers a detailed exploration of engineering and materials science, and examines the boundary and relationship between the two. Based on the author’s course lecture notes and many years of research, it presents students with the knowledge needed to select and design biomaterials used in medical devices. Placing special emphasis on metallic, ceramic, polymeric, and composite biomaterials, it explains the difference between materials science and materials engineering, introduces basic concepts and principle...
Cell Apoptosis Research Progress
Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This title looks at research into this programmed cell death.
