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Apoptosis in Carcinogenesis and Chemotherapy
Although research on carcinogenesis has focused more on cellular proliferation than on cell death, yet understanding the mechanism of apoptosis may have important implications for cancer therapy. This book brings together experts from around the world who will discuss the common cancers encountered in clinical practice in the laboratory setting. During the induction of these common cancers, the role of apoptosis in cellular and molecular changes is emphasized, critically highlighting possible anti-cancer strategies. For those who are interested in carcinogenesis and for those who are seeking new approaches to anti-cancer therapy, this book is an important reference. It serves not only as a r...
The Pioneer Adventures of Chen Sing
Embark on the thrilling sequel to The Railroad Adventures of Chen Sing. Join him after his railroad-building days, where he confronts natural disasters, encounters wild animals, and navigates unforeseen events at every turn. Chen Sing must summon courage and perseverance to establish his legacy as a true pioneer.
Winning at the Turning Point
This book by influential policymaker Chi Fulin lays out in issue-oriented and detailed chapters, at a time when China is at a crossroads, exactly how the government plans to deal with the social, political and economic issues the world's second-largest economy faces. From managing the decline of industry, to urbanization, to managing consumption, to social security and education, Chi offers a roadmap for the years ahead. This book will be particularly fascinating to Western scholars of China who speculate on the inner workings of the Chinese policymaking elite, with the ambition of China's central planners here laid out for the world to see.
Novel Apoptotic Regulators in Carcinogenesis
Our recent understanding of the cellular and molecular defects and the regulation of the apoptotic signalling pathways has resulted in rationally designed anticancer strategies and the development of novel agents that regulates apoptosis. A comprehensive review of all apoptotic-related anticancer therapies is not the purpose of this book. However, in the volume of this book with 11 chapters, we have described a number of novel apoptotic regulators that have shown promising value and also great feasibility for cancer treatment. These novel agents either occur naturally or are chemically synthesized. While we are excited about the discovery and development of these novel apoptotic regulators a...
Advances in Cancer Drug Targets
Advances in Cancer Drug Targets is an e-book series that brings together recent expert reviews published on the subject with a focus on strategies for synthesizing and isolating organic compounds and elucidating the structure and nature of DNA. The reviews presented in this series are written by experts in pharmaceutical sciences and molecular biology. These reviews have been carefully selected to present development of new approaches to anti-cancer therapy and anti-cancer drug development. The contents of this book include chapters on heat shock protein 90, spindle assembly checkpoint, ErbB receptors, anti-tumor effects of bisphosphonates, biomarkers for risk assessment and prevention of breast cancer, fibrates action in Daunorubicin chemical reaction and many more. The reference work serves to give readers a brief yet comprehensive glance at current theory and practice behind employing chemical compounds for tackling tumor suppression, DNA site specific drug targeting and the inhibition of enzymes involved in growth control pathways. This e-book volume will be of special interest to molecular biologists and pharmaceutical scientists.
Oncogene Proteins
Oncogene proteins are proteins coded by oncogenes. They include proteins resulting from the fusion of an oncogene and another gene (oncogene proteins, fusion). An oncogene is a modified gene, or a set of nucleotides that codes for a protein and is believed to cause cancer. This book brings together the latest research in this field from around the world.
Cell Apoptosis Research Progress
Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This title looks at research into this programmed cell death.
Cancer Drug Resistance Research Perspectives
One of the main causes of failure in the treatment of cancer is the development of drug resistance by the cancer cells. The design of cancer chemotherapy has become increasingly sophisticated, yet there is no cancer treatment that is 100% effective against disseminated cancer. Resistance to treatment with anticancer drugs results from a variety of factors including individual variations in patients and somatic cell genetic differences in tumours, even those from the same tissue of origin. Frequently resistance is intrinsic to the cancer, but as therapy becomes more and more effective, acquired resistance has also become common. The most common reason for acquisition of resistance to a broad ...
All Dinosaurs Die
George Chen has taught Biology classes at the University of California, San Diego for the last three years. In that time he has amassed a collection of student responses to increasingly ridiculous questions. The best of these responses have been selected for this compilation.
